1, 25-Dihydroxvitamin D3 [1, 25 (OH) 2D3] is the hormonally active form of vitamin D. The
genomic mechanism of 1, 25 (OH) 2D3 action involves the direct binding of the 1, 25 (OH) …

Although mitochondria are best known for being the eukaryotic cell powerhouses, these
organelles participate in various cellular functions besides ATP production, such as calcium …

In the last 5 years, there has been a remarkable change in our understanding of the health
benefits of vitamin D. The classical actions of vitamin D as a determinant of mineral …

Vitamin D3 (cholecalciferol) is taken in the diet (from fortified dairy products and fish oils) or
is synthesized in the skin from 7-dehydrocholesterol by ultraviolet irradiation. The vitamin D …

Inflammation is associated with a number of chronic conditions, such as cancer and
cardiovascular disease. Reducing inflammation may help prevent or treat these conditions …

Immunomodulatory actions of vitamin D have been recognised for over a quarter of a
century, but it is only in the last few years that the significance of this to normal human …

Interaction between vitamin D and the immune system has been recognized for many years,
but its relevance to normal human physiology has only become evident in the past 5 years …

The purpose of studying the epidemiology of multiple sclerosis (MS) is twofold. First, it is
important to understand clearly the natural history of the illness in order to assist patients in …

This critical time frame of intrauterine life development is considered of major importance on
the metabolic imprinting of overall health of the offspring, in later life. This requires a delicate …

Vitamin D is a pleiotropic secosteroid hormone important for health and disease prevention.
The actions of vitamin D are mediated by the vitamin D receptor that binds the active form of …