In recent years, circular RNAs (circRNAs), a new class of RNA molecules characterized by
their covalently closed circular structure, have become a new research paradigm in RNA …

Abstract Circular RNAs (CircRNAs) are a class of single-stranded noncoding RNAs that are
formed in a circular conformation via non-canonical splicing or back-splicing events …

Majority of the human genome is transcribed to RNAs that do not encode proteins. These
non-coding RNAs (ncRNAs) play crucial roles in regulating the initiation and progression of …

The nuclear factor-kappaB (NF-κB) signaling pathway is considered as a potential
therapeutic target in cancer therapy. It has been well established that transcription factor NF …

Nanotechnology is a growing field, with many potential biomedical applications of
nanomedicine for the treatment of different diseases, particularly cancer, on the horizon …

The resistance of tumor cells to therapy severely impairs the efficacy of treatment, leading to
recurrence and metastasis of various cancers. Clarifying the underlying mechanisms of …

Among cancers, breast cancer has the highest incidence rate among women and poses a
tremendous threat to women's health. Messenger RNA (mRNA), microRNA (miRNA) and …

Background Laryngeal squamous cell carcinoma (LSCC) is the second most common
malignant tumor in head and neck. Autophagy and circular RNAs (circRNAs) play critical …

Blood-brain barrier (BBB) damage can be a result of central nervous system (CNS) diseases
and may be a cause of CNS deterioration. However, there are still many unknowns …

Background Previous studies have shown that the N6-methyladenosine (m6A) modification
enhances the binding ability of mRNAs/long noncoding RNAs (lncRNAs) to microRNAs …