TRAUMATIC BRAIN INJURY–INDUCED INFLAMMATION AND GASTROINTESTINAL MOTILITY DYSFUNCTION

AR Cannon, LJ Anderson, K Galicia, MG Murray… - Shock, 2023 - journals.lww.com
Background: Traumatic brain injury (TBI) is a significant cause of morbidity and mortality in
the United States, with an annual cost of 60 billion dollars. There is evidence suggesting that …

Multimodal treatment approaches to combined traumatic brain injury and hemorrhagic shock alter postinjury inflammatory response

TE Wallen, MR Baucom, LG England, RM Schuster… - Shock, 2022 - journals.lww.com
Introduction: The optimal management strategies for patients with polytraumatic injuries that
include traumatic brain injury (TBI) are not well defined. Specific interventions including …

Defining endotheliopathy in murine polytrauma models

TE Wallen, KE Singer, NC Elson, MR Baucom… - Shock, 2022 - journals.lww.com
Methods: Mice were randomized to undergo moderately severe concussive TBI by weight
drop, 60-min hemorrhagic shock to MAP 25 mmHg with subsequent resuscitation with …

Allopurinol attenuates repeated traumatic brain injury in old rats: A preliminary report

D Kaya, SC Micili, C Kizmazoglu, AO Mucuoglu… - Experimental …, 2022 - Elsevier
Traumatic brain injury (TBI) is an overlooked cause of morbidity, which was shown to
accelerate inflammation, oxidative stress, and neuronal cell loss and is associated with …

Postinjury treatment to mitigate the effects of aeromedical evacuation after traumatic brain injury in a porcine model

MR Baucom, TE Wallen, KE Singer, J Youngs… - Journal of Surgical …, 2022 - Elsevier
Introduction Early aeromedical evacuation after traumatic brain injury (TBI) has been
associated with worse neurologic outcomes in murine studies and military populations. The …

Murine traumatic brain injury model comparison: closed head injury versus controlled cortical impact

MR Baucom, AD Price, L England, RM Schuster… - Journal of surgical …, 2024 - Elsevier
Introduction Various murine models have been utilized to study TBI, including closed head
injury (CHI) and controlled cortical impact (CCI), without direct comparison. The aim of our …

Effects of sequential aeromedical evacuations following traumatic brain injury in swine

FG Arnaud, LTA Haque, MAJE Barkei, MAJE Morris… - Injury, 2022 - Elsevier
Introduction Traumatic brain injuries (TBI) represent a significant percentage of critical
injuries in military conflicts. Following injury, wounded warfighters are often subjected to …

Effects of antifibrinolytics on systemic and cerebral inflammation after traumatic brain injury

TE Wallen, KE Singer, MR Baucom… - Journal of Trauma …, 2022 - journals.lww.com
BACKGROUND Administration of antifibrinolytic medications, including tranexamic acid
(TXA), may reduce head injury–related mortality. The effect of these medications on post …

[PDF][PDF] ОСОБЛИВОСТІ ЗМІН ПОКАЗНИКІВ ГЕМОДИНАМІКИ У ПОСТРАЖДАЛИХ ІЗ МІННО-ВИБУХОВИМИ ПРОНИКАЮЧИМИ ПОРАНЕННЯМИ ГОЛОВИ ПІД …

Г Хитрий, Ю Ухач - Перспективи та інновації науки, 2023 - perspectives.pp.ua
В дослідженні проведено ретроспективний аналіз медичної документації 70
постраждалих із мінно-вибуховими проникаючими пораненнями голови, які були …