[HTML][HTML] Ginsenoside Rk3 is a novel PI3K/AKT-targeting therapeutics agent that regulates autophagy and apoptosis in hepatocellular carcinoma
L Qu, Y Liu, J Deng, X Ma, D Fan - Journal of Pharmaceutical Analysis, 2023 - Elsevier
Hepatocellular carcinoma (HCC) is the third leading cause of cancer death worldwide.
Ginsenoside Rk3, an important and rare saponin in heat-treated ginseng, is generated from …
Ginsenoside Rk3, an important and rare saponin in heat-treated ginseng, is generated from …
Novel 1, 3, 5-triazine-based pyrazole derivatives as potential antitumor agents and EFGR kinase inhibitors: Synthesis, cytotoxicity, DNA binding, molecular docking …
We herein report the design and synthesis of new 1, 3, 5-triazine-based pyrazole derivatives
(5a–i) with anticancer activity targeting the epidermal growth factor (EGFR) tyrosine kinase …
(5a–i) with anticancer activity targeting the epidermal growth factor (EGFR) tyrosine kinase …
[HTML][HTML] A pan-cancer analysis of GINS complex subunit 4 to identify its potential role as a biomarker in multiple human cancers
M Usman, MK Okla, HM Asif… - American Journal of …, 2022 - ncbi.nlm.nih.gov
This study was initiated to explore the expression variation, clinical significance, and
biological importance of the GINS complex subunit 4 (GINS4) in different human cancers as …
biological importance of the GINS complex subunit 4 (GINS4) in different human cancers as …
HIF-2α-targeted interventional chemoembolization multifunctional microspheres for effective elimination of hepatocellular carcinoma
M Chen, G Shu, X Lv, X Xu, C Lu, E Qiao, S Fang… - Biomaterials, 2022 - Elsevier
Transcatheter arterial chemoembolization (TACE) is widely used for the treatment of
advanced hepatocellular carcinoma (HCC). However, the long-term hypoxic …
advanced hepatocellular carcinoma (HCC). However, the long-term hypoxic …
Asparanin A from Asparagus officinalis L. Induces G0/G1 Cell Cycle Arrest and Apoptosis in Human Endometrial Carcinoma Ishikawa Cells via Mitochondrial and …
F Zhang, YY Zhang, YS Sun, RH Ma… - Journal of Agricultural …, 2019 - ACS Publications
Asparanin A (AA), a steroidal saponin from Asparagus officinalis L., has anticancer activity:
however, its detailed molecular mechanisms in endometrial cancer (EC) have not been …
however, its detailed molecular mechanisms in endometrial cancer (EC) have not been …
[HTML][HTML] Interactions of multidomain pro-apoptotic and anti-apoptotic proteins in cancer cell death
Cancer is a global public health concern that is characterized by the uncontrolled growth of
tumor cells. It is regarded as the subsequent cause of death after cardiovascular disease …
tumor cells. It is regarded as the subsequent cause of death after cardiovascular disease …
[HTML][HTML] A review on metal complexes and its anti-cancer activities: Recent updates from in vivo studies
Research into cancer therapeutics has uncovered various potential medications based on
metal-containing scaffolds after the discovery and clinical applications of cisplatin as an anti …
metal-containing scaffolds after the discovery and clinical applications of cisplatin as an anti …
[HTML][HTML] Induction of G2/M cell cycle arrest and apoptosis by genistein in human bladder cancer T24 cells through inhibition of the ROS-dependent PI3k/Akt signal …
We examined the anti-cancer effect of genistein, a soy-derived isoflavone, in human bladder
transitional cell carcinoma T24 cells. According to our data, genistein induced G2/M phase …
transitional cell carcinoma T24 cells. According to our data, genistein induced G2/M phase …
[HTML][HTML] Molecular design, synthesis and anticancer activity of new thiopyrano [2, 3-d] thiazoles based on 5-hydroxy-1, 4-naphthoquinone (juglone)
I Ivasechko, A Lozynskyi, J Senkiv… - European journal of …, 2023 - Elsevier
Abstract A series of 11-substituted 9-hydroxy-3, 5, 10, 11-tetrahydro-2H-benzo [6, 7]
thiochromeno [2, 3-d][1, 3] thiazole-2, 5, 10-triones 3.1–3.13 were synthesized via hetero …
thiochromeno [2, 3-d][1, 3] thiazole-2, 5, 10-triones 3.1–3.13 were synthesized via hetero …
New manganese (II), iron (II), cobalt (II), nickel (II) and copper (II) saccharinate complexes of 2, 6-bis (2-benzimidazolyl) pyridine as potential anticancer agents
New mononuclear complexes [Mn (NO 3)(sac)(H 2 O)(bzimpy)]· 2DMF (Mn),[Fe (sac) 2 (H 2
O)(bzimpy)]· 2H 2 O (Fe),[Co (bzimpy) 2](sac) 2· 2H 2 O (Co),[Ni (bzimpy) 2](sac) 2· H 2 O· i …
O)(bzimpy)]· 2H 2 O (Fe),[Co (bzimpy) 2](sac) 2· 2H 2 O (Co),[Ni (bzimpy) 2](sac) 2· H 2 O· i …