Abstract Neoplasm (Glioblastoma) and Alzheimer's disease (AD) comprise two of the most
chronic psychological ailments. Glioblastoma is one of the aggressive and prevalent …

Withanolides are a class of natural products with a steroidal lactone structure that exhibit a
broad spectrum of anti-cancer effects. To date, several studies have shown that their …

A new series of hybrid compounds with tropinone and thiazole rings in the structure was
designed and synthesized as potential anticancer agents. They were tested against human …

Cancer therapy using immune checkpoint inhibitors (ICIs) is a promising clinical strategy for
patients with multiple types of cancer. The expression of programmed cell death ligand-1 …

A small library of novel 1, 3, 4-oxadiazole bioisosteres was synthesized and their cytotoxic
activity evaluated in vitro. Five of the new derivatives (3, 6, 11, 14 and 15) showed high …

A large body of evidence indicates that lignans as polyphenolic compounds are beneficial
against life-threatening diseases such as cancer. Plant lignans have the potential to induce …

Cancer is a complex disease that remains a leading cause of death worldwide owing to the
lack of effective and efficient drugs. Compounds known as tetrahydropyrmidine have shown …

Background One of the significant morbidity and mortality causes is the colorectal cancer.
Rosmarinus officinalis plant is utilized as food and medicine. Currently, nanoparticles are …

Background Breast cancer (BC) is a complex disease with various subtypes and genetic
alterations that impact DNA repair pathways. Understanding these pathways is essential for …

Rosavin is an alkylbenzene diglycoside primarily found in Rhodiola rosea (L.),
demonstrating various pharmacological properties in a number of preclinical test systems …