Design, synthesis, structure-activity relationships and mechanism of action of new quinoline derivatives as potential antitumor agents
S Li, L Hu, J Li, J Zhu, F Zeng, Q Huang, L Qiu… - European Journal of …, 2019 - Elsevier
A series of new quinoline derivatives was designed, synthesized and evaluated as potential
antitumor agents. The results indicated that most compounds exhibited potent …
antitumor agents. The results indicated that most compounds exhibited potent …
[HTML][HTML] ATM in breast and brain tumors: a comprehensive review
MA Estiar, P Mehdipour - Cancer biology & medicine, 2018 - ncbi.nlm.nih.gov
The ATM gene is mutated in the syndrome, ataxia-telangiectasia (AT), which is
characterized by predisposition to cancer. Patients with AT have an elevated risk of breast …
characterized by predisposition to cancer. Patients with AT have an elevated risk of breast …
Cytotoxic and proapoptotic effect of doxycycline–An in vitro study on the human skin melanoma cells
J Rok, M Karkoszka, Z Rzepka, M Respondek… - Toxicology in Vitro, 2020 - Elsevier
Doxycycline is a semisynthetic, second generation tetracycline. Currently, it is used, among
others, in the treatment of acne and skin infections. Moreover, doxycycline has many …
others, in the treatment of acne and skin infections. Moreover, doxycycline has many …
A novel drug delivery system: The encapsulation of naringenin in metal-organic frameworks into liposomes
Z Wang, L Liu, W Yin, Z Liu, L Shi, M Tang - AAPS PharmSciTech, 2021 - Springer
Poorly water-soluble naringenin (NAR) was selected as a model drug and loaded into the
porous MOFs for the construction of NAR@ ZIF-8 inclusion complex. By film dispersion …
porous MOFs for the construction of NAR@ ZIF-8 inclusion complex. By film dispersion …
Compound K: A systematic review of its anticancer properties and probable mechanisms
Panax ginseng is a common natural product, which is well‐known to have a wide range of
pharmacological activities in cancer. Its metabolite, compound K (CK), has been reported to …
pharmacological activities in cancer. Its metabolite, compound K (CK), has been reported to …
Nanomedicine Advancements: Vanadium Oxide Nanoparticles as a Game-Changer in Antimicrobial and Anticancer Therapies
This review examines nanomedicine's dynamic landscape, emphasizing vanadium oxide
nanoparticles (V 2 O 5 NPs) and their pivotal role in antimicrobial and anticancer therapies …
nanoparticles (V 2 O 5 NPs) and their pivotal role in antimicrobial and anticancer therapies …
Apoptosis-mediated anti-proliferative activity of Calligonum comosum against human breast cancer cells, and molecular docking of its major polyphenolics to …
Due to poor diagnosis breast cancer in women has emerged as the most common cause of
death disease in developing countries. Medicinal plants have been used for thousands of …
death disease in developing countries. Medicinal plants have been used for thousands of …
[HTML][HTML] Podophyllotoxin induces ROS-mediated apoptosis and cell cycle arrest in human colorectal cancer cells via p38 MAPK signaling
Podophyllotoxin (PT), a lignan compound from the roots and rhizomes of Podophyllum
peltatum, has diverse pharmacological activities including anticancer effect in several types …
peltatum, has diverse pharmacological activities including anticancer effect in several types …
[HTML][HTML] Cordycepin inhibits the proliferation of malignant peripheral nerve sheath tumor cells through the p53/Sp1/tubulin pathway
MJ Lee, JC Lee, JH Hsieh, MY Lin, IA Shih… - American Journal of …, 2021 - ncbi.nlm.nih.gov
Abstract Neurofibromatosis type 1 (NF1) is one of the most common hereditary
neurocutaneous disorders. In addition to skin pigmentation and cutaneous neurofibroma …
neurocutaneous disorders. In addition to skin pigmentation and cutaneous neurofibroma …
Involvement of phytochemical-encapsulated nanoparticles' interaction with cellular signalling in the amelioration of benign and malignant brain tumours
Brain tumours have unresolved challenges that include delay prognosis and lower patient
survival rate. The increased understanding of the molecular pathways underlying cancer …
survival rate. The increased understanding of the molecular pathways underlying cancer …