[HTML][HTML] Anaplastic thyroid cancer: molecular pathogenesis and emerging therapies

RC Smallridge, LA Marlow… - Endocrine-related …, 2009 - erc.bioscientifica.com
Anaplastic thyroid cancer (ATC) is a rare malignancy. While external beam radiation therapy
has improved locoregional control, the median survival of∼ 4 months has not changed in …

Thyroid papillary microcarcinoma: a descriptive and meta-analysis study

E Roti, EC degli Uberti, M Bondanelli… - European Journal of …, 2008 - academic.oup.com
The authors review anatomical, clinical characteristics and prevalence of thyroid
microcarcinoma. Diagnostic procedures and risk factors of aggressiveness at diagnosis and …

[HTML][HTML] Pathogenesis, diagnosis and management of thyroid nodules in children

M Niedziela - Endocrine-related cancer, 2006 - erc.bioscientifica.com
According to the literature thyroid nodules are quite rare in the first two decades of life.
However, there are some exceptions, relating to areas with an iodine deficiency or affected …

[HTML][HTML] Thyroid carcinoma: molecular pathways and therapeutic targets

YE Nikiforov - Modern Pathology, 2008 - Elsevier
Thyroid cancer is the most common malignant tumor of the endocrine system. The most
frequent type of thyroid malignancy is papillary carcinoma. These tumors frequently have …

A narrative review of genetic alterations in primary thyroid epithelial cancer

C Romei, R Elisei - International journal of molecular sciences, 2021 - mdpi.com
Thyroid carcinoma is the most frequent endocrine neoplasia. Different types of thyroid
carcinoma are described: well-differentiated papillary thyroid carcinoma (PTC), poorly …

Molecular diagnostics of thyroid tumors

YE Nikiforov - Archives of pathology & laboratory medicine, 2011 - meridian.allenpress.com
Context.—Thyroid cancer is the most common type of endocrine malignancy and its
incidence is steadily increasing. Papillary carcinoma and follicular carcinoma are the most …

[HTML][HTML] Oncogenic AKAP9-BRAF fusion is a novel mechanism of MAPK pathway activation in thyroid cancer

R Ciampi, JA Knauf, R Kerler, M Gandhi… - The Journal of …, 2005 - Am Soc Clin Investig
Genes crucial for cancer development can be mutated via various mechanisms, which may
reflect the nature of the mutagen. In thyroid papillary carcinomas, mutations of genes coding …

The BRAFV600E Mutation Is an Independent, Poor Prognostic Factor for the Outcome of Patients with Low-Risk Intrathyroid Papillary Thyroid Carcinoma: Single …

R Elisei, D Viola, L Torregrossa… - The Journal of …, 2012 - academic.oup.com
Background: The BRAF V600E mutation, the most frequent genetic alteration in papillary
thyroid carcinoma (PTC), was demonstrated to be a poor prognostic factor. The aim of this …

Targeted Expression of BRAFV600E in Thyroid Cells of Transgenic Mice Results in Papillary Thyroid Cancers that Undergo Dedifferentiation

JA Knauf, X Ma, EP Smith, L Zhang, N Mitsutake… - Cancer research, 2005 - AACR
The BRAFT1799A mutation is the most common genetic alteration in papillary thyroid
carcinomas (PTC). It is also found in a subset of papillary microcarcinomas, consistent with a …

Molecular diagnostics and predictors in thyroid cancer

MN Nikiforova, YE Nikiforov - Thyroid, 2009 - liebertpub.com
Background: The accuracy of cancer detection in thyroid nodules by fine-needle aspiration
(FNA) cytology and prognostication of thyroid cancer needs further improvement and can …