BACKGROUND:“Follicular lesion of undetermined significance/atypia of undetermined
significance” is a heterogeneous category of cases that cannot be classified into 1 of the …

Papillary thyroid carcinoma (PTC) is associated with RET and NTRK1 rearrangements and
BRAF mutations. A series of 60 PTCs collected in a single center from Italian patients were …

This article reviews the small percentage of thyroid tumours that are not classified as classic
papillary thyroid carcinoma, follicular thyroid carcinoma, and medullary thyroid carcinoma. It …

Background The objective of this study is to perform a meta-analysis to evaluate the
associations between the BRAF V600E mutation status and aggressive clinicopathological …

The incidence of melanoma is increasing at one of the highest rates of any form of cancer in
the United States, with the current lifetime risk being one in 68. At present, there are limited …

Summary Background The activating BRAFV600E mutation is the most common genetic
alteration reported in papillary thyroid carcinoma (PTC). While some reports suggest the …

Background: Very little was known about the molecular pathogenesis of thyroid cancer until
the late 1980s. As part of the Centennial celebration of the American Thyroid Association …

Activating mutations of BRAF have been identified in a variety of human cancers, most
notably melanomas and papillary thyroid carcinomas (PTCs). The aim of the present study …

BRAF represents one of the most frequently mutated protein kinase genes in human
tumours. The mutation is commonly tested in pathology practice. BRAF mutation is seen in …

In the recent years, a large number of molecular alterations in thyroid cancer has been
discovered and characterized. Some of these markers may have significant diagnostic utility …