Galectins are a family of animal lectins with diverse biological activities. They function both
extracellularly, by interacting with cell-surface and extracellular matrix glycoproteins and …

Galectins are widely distributed sugar-binding proteins whose basic specificity for β-
galactosides is conserved by evolutionarily preserved carbohydrate-recognition domains …

Galectins are a family of carbohydrate-binding proteins with an affinity for β-galactosides.
Galectin-1 (Gal-1) is differentially expressed by various normal and pathological tissues and …

Lectins are carbohydrate-binding proteins which lack enzymatic activity on their ligand and
are distinct from antibodies and free mono-and oligosaccharide sensor/transport proteins …

The modular synthesis of 7 libraries containing 51 self-assembling amphiphilic Janus
dendrimers with the monosaccharides d-mannose and d-galactose and the disaccharide d …

GM1 ganglioside occurs widely in vertebrate tissues, where it exhibits many essential
functions, both in the plasma membrane and intracellular loci. Its essentiality is revealed in …

Galectin-3 is unique among the galectin family of animal lectins in its biological activities and
structure. Most members of the galectin family including galectin-1 possess apoptotic …

Growing insights into the many roles of glycoconjugates in biorecognition as ligands for
lectins indicates a need to compare plant and animal lectins. Furthermore, the popularity of …

Lipid rafts, sites of signal transduction, are enriched in glycosphingolipids (GSLs).
Gangliosides, a class of GSLs found in greatest concentration in the grey matter of the brain …

Despite the existence of tumor-specific immune cells, most tumors have devised strategies
to avoid immune attack. We demonstrate here that galectin-1 (Gal-1), a negative regulator of …