[HTML][HTML] Role of primary aging hallmarks in Alzheimer´ s disease
J Zhao, J Huai - Theranostics, 2023 - ncbi.nlm.nih.gov
Alzheimer's disease (AD) is the most common neurodegenerative disease, which severely
threatens the health of the elderly and causes significant economic and social burdens. The …
threatens the health of the elderly and causes significant economic and social burdens. The …
[HTML][HTML] The interaction between ageing and Alzheimer's disease: insights from the hallmarks of ageing
Ageing is a crucial risk factor for Alzheimer's disease (AD) and is characterised by systemic
changes in both intracellular and extracellular microenvironments that affect the entire body …
changes in both intracellular and extracellular microenvironments that affect the entire body …
[HTML][HTML] Decreased MEF2A expression regulated by its enhancer methylation inhibits autophagy and may play an important role in the progression of Alzheimer's …
H Li, F Wang, X Guo, Y Jiang - Frontiers in neuroscience, 2021 - frontiersin.org
Alzheimer's disease (AD) is a neurodegenerative disease characterized by amyloid plaques
and neurofibrillary tangles which significantly affects people's life quality. Recently, AD has …
and neurofibrillary tangles which significantly affects people's life quality. Recently, AD has …
Neurodevelopmental toxicity induced by PM2. 5 Exposure and its possible role in Neurodegenerative and mental disorders
X Liu, J Huang, C Song, T Zhang… - Human & …, 2023 - journals.sagepub.com
Recent extensive evidence suggests that ambient fine particulate matter (PM2. 5, with an
aerodynamic diameter≤ 2.5 μm) may be neurotoxic to the brain and cause central nervous …
aerodynamic diameter≤ 2.5 μm) may be neurotoxic to the brain and cause central nervous …
[HTML][HTML] Neuroprotective Epigenetic Changes Induced by Maternal Treatment with an Inhibitor of Soluble Epoxide Hydrolase Prevents Early Alzheimer′ s Disease …
C Bartra, A Irisarri, A Villoslada, R Corpas… - International Journal of …, 2022 - mdpi.com
Modulation of Alzheimer′ s disease (AD) risk begins early in life. During embryo
development and postnatal maturation, the brain receives maternal physiological influences …
development and postnatal maturation, the brain receives maternal physiological influences …
ABCA7-Associated Clinical Features and Molecular Mechanisms in Alzheimer's Disease
X Qian, S Chen, X Liu, H Tang - Molecular Neurobiology, 2023 - Springer
Alzheimer's disease (AD) is the most common type of neurodegenerative disease and its
pathogenesis is still unclear. Genetic factors are thought to account for a large proportion of …
pathogenesis is still unclear. Genetic factors are thought to account for a large proportion of …
[HTML][HTML] Advances in the role of the GADD45 family in neurodevelopmental, neurodegenerative, and neuropsychiatric disorders
M Huang, J Wang, W Liu, H Zhou - Frontiers in Neuroscience, 2024 - frontiersin.org
The growth arrest and DNA damage inducible protein 45 (GADD45) family comprises stress-
induced nuclear proteins that interact with DNA demethylases to facilitate DNA …
induced nuclear proteins that interact with DNA demethylases to facilitate DNA …
Curcumin can improve spinal cord injury by inhibiting DNA methylation
Y Zhou, Y Zhang, BOA Botchway, X Wang… - Molecular and Cellular …, 2024 - Springer
Spinal cord injury (SCI) is a serious central nervous system disease. Traumatic SCI often
causes persistent neurological deficits below the injury level. Epigenetic changes occur after …
causes persistent neurological deficits below the injury level. Epigenetic changes occur after …
[HTML][HTML] Restoring the epigenome in Alzheimer's disease: Advancing HDAC inhibitors as therapeutic agents
M Pereira, MT Cruz, A Fortuna, J Bicker - Drug Discovery Today, 2024 - Elsevier
Current treatment options for Alzheimer's disease (AD) focus on symptom relief rather than
halting disease progression. In this context, targeting histone deacetylation emerges as a …
halting disease progression. In this context, targeting histone deacetylation emerges as a …
[HTML][HTML] LncRNA XR_351665 Contributes to Chronic Pain-Induced Depression by Upregulating DNMT1 via Sponging miR-152-3p
X Ding, Y Lin, B Yan, X Jiao, Q Liu, H Miao, Y Wu… - The Journal of …, 2023 - Elsevier
Chronic pain is frequently comorbid with depression. However, the mechanisms underlying
chronic pain-induced depression remain unclear. Here, we found that DNA …
chronic pain-induced depression remain unclear. Here, we found that DNA …