[PDF][PDF] Involvement of nucleic-acid methylation on biology and evolution: from first hominids to modern humans–Review

G Dorado, F Luque, FJ Esteban, P Pascual… - …, 2022 - researchgate.net
Recent developments in molecular biology, in general, and nucleic-acid sequencing, in
particular, have allowed fascinating discoveries. Thus, it is now known that DNA and RNA …

Epigenetic programming of human disease and aging

NA Rivero-Segura, D Castro-Morales… - Epigenetics in Human …, 2024 - Elsevier
As many authors state, aging has been conceptualized as a biological process that leads to
declining function and increases the susceptibility to age-related diseases such as cancer …

[PDF][PDF] Twenty-year longitudinal evaluation of blood-based DNA methylation biomarkers for early prediction of Alzheimer's disease

FS Hackenhaar, M Josefsson, AN Adolfsson… - 2022 - scholar.archive.org
Background: DNA methylation (DNAm) is an epigenetic mechanism re ecting both inherited
and environmental in uences, and is a promising biomarker of multifactorial aging-related …

[HTML][HTML] Blood DNA methylation levels in the WNT5A gene promoter region: a potential biomarker for agitation in subjects with dementia

N Kobayashi, S Shinagawa, T Nagata… - Journal of …, 2021 - content.iospress.com
Background: Behavioral and psychological symptoms of dementia (BPSD) cause a heavy
burden for both patient and caregivers. These symptoms are diverse, and their mechanism …

[HTML][HTML] Direct Conversion of Fibroblast into Neurons for Alzheimer's Disease Research: A Systematic Review

R Sattarov, H Toresson, C Orbjörn… - Journal of …, 2023 - content.iospress.com
Background: Alzheimer's disease (AD) is a prevalent neurodegenerative disorder without a
cure. Innovative disease models, such as induced neurons (iNs), could enhance our …

Implicación de la metilación de ácidos nucleicos en biología y evolución: desde los primeros homínidos hasta los humanos modernos: Revisión

G Dorado, F Luque, FJ Esteban, P Pascual… - …, 2022 - dialnet.unirioja.es
Los avances recientes en biología molecular, en general, y secuenciación de ácidos
nucleicos, en particular, han posibilitado descubrimientos fascinantes. Así, ahora se sabe …

[HTML][HTML] The role of TDG-mediated DNA demethylation in the entorhinal-hippocampal spatial representation system

KS Innvær - 2022 - ntnuopen.ntnu.no
Cognitive impairments and memory decline are commonly seen with aging. The decline is
often seen with epigenetic alterations, such as in DNA methylation and demethylation …

Assessing the Role of TDG in the Hippocampus-dependent Memory using Transgenic Mouse Models and rAAV Viral Tools

DS Døskeland - 2022 - ntnuopen.ntnu.no
Thymine DNA glycosylase (TDG) is a vital enzyme with dual roles in genome maintenance
and epigenetic regulation. Emerging evidence indicates an essential role of TDG in active …

Parameters that determine the direction of transcription

F Uchiumi - Bidirectional Gene Promoters: Transcription System …, 2022 - books.google.com
To talk about the world before living things appeared on the ancient Earth, we might better
accept that it started as the RNA world. Presently, the RNA polymers function as primary …

[PDF][PDF] The Effect of Eight Weeks of Training on Positive and Negative Slopes with Royal Jelly Consumption on MGMT and ATPase Gene Expression Levels in the …

Z Giti, A Banaeifar, S Arshadi… - Gene, Cell and …, 2022 - brieflands.com
Background: Alzheimer's disease (AD) is a common disease in the elderly that is associated
with impaired metabolism and biology of the hippocampus. Although the role of exercise …