Chemical Biology of H2S Signaling through Persulfidation
MR Filipovic, J Zivanovic, B Alvarez… - Chemical …, 2018 - ACS Publications
Signaling by H2S is proposed to occur via persulfidation, a posttranslational modification of
cysteine residues (RSH) to persulfides (RSSH). Persulfidation provides a framework for …
cysteine residues (RSH) to persulfides (RSSH). Persulfidation provides a framework for …
[HTML][HTML] The emerging hallmarks of cancer metabolism
NN Pavlova, CB Thompson - Cell metabolism, 2016 - cell.com
Tumorigenesis is dependent on the reprogramming of cellular metabolism as both direct
and indirect consequence of oncogenic mutations. A common feature of cancer cell …
and indirect consequence of oncogenic mutations. A common feature of cancer cell …
Targeted contrast agents and activatable probes for photoacoustic imaging of cancer
Z Zhao, CB Swartchick, J Chan - Chemical Society Reviews, 2022 - pubs.rsc.org
Photoacoustic (PA) imaging has emerged as a powerful technique for the high resolution
visualization of biological processes within deep tissue. Through the development and …
visualization of biological processes within deep tissue. Through the development and …
[HTML][HTML] Hydrogen sulfide: An endogenous regulator of the immune system
N Dilek, A Papapetropoulos, T Toliver-Kinsky… - Pharmacological …, 2020 - Elsevier
Hydrogen sulfide (H 2 S) is now recognized as an endogenous signaling gasotransmitter in
mammals. It is produced by mammalian cells and tissues by various enzymes …
mammals. It is produced by mammalian cells and tissues by various enzymes …
A review of hydrogen sulfide synthesis, metabolism, and measurement: is modulation of hydrogen sulfide a novel therapeutic for cancer?
X Cao, L Ding, Z Xie, Y Yang, M Whiteman… - Antioxidants & redox …, 2019 - liebertpub.com
Abstract Significance: Hydrogen sulfide (H2S) has been recognized as the third gaseous
transmitter alongside nitric oxide and carbon monoxide. In the past decade, numerous …
transmitter alongside nitric oxide and carbon monoxide. In the past decade, numerous …
Stimuli‐responsive NO release for on‐demand gas‐sensitized synergistic cancer therapy
Featuring high biocompatibility, the emerging field of gas therapy has attracted extensive
attention in the medical and scientific communities. Currently, considerable research has …
attention in the medical and scientific communities. Currently, considerable research has …
Redox regulation and its emerging roles in cancer treatment
H Zhang, Z Mao, Y Kang, W Zhang, L Mei… - Coordination Chemistry …, 2023 - Elsevier
Intracellular reduction–oxidation (redox) homeostasis, mediated mainly by reactive oxygen
species (ROS), plays a significant role in physiological function maintenance and regulation …
species (ROS), plays a significant role in physiological function maintenance and regulation …
[HTML][HTML] H2S-activatable near-infrared afterglow luminescent probes for sensitive molecular imaging in vivo
L Wu, Y Ishigaki, Y Hu, K Sugimoto, W Zeng… - Nature …, 2020 - nature.com
Afterglow luminescent probes with high signal-to-background ratio show promise for in vivo
imaging; however, such probes that can be selectively delivered into target sites and switch …
imaging; however, such probes that can be selectively delivered into target sites and switch …
Zwitterion‐Based hydrogen sulfide nanomotors induce multiple acidosis in tumor cells by destroying tumor metabolic symbiosis
M Wan, Z Liu, T Li, H Chen, Q Wang… - Angewandte …, 2021 - Wiley Online Library
Destruction of tumor metabolism symbiosis is an attractive cancer treatment method which
targets tumor cells with little harm to normal cells. Yet, a single intervention strategy and poor …
targets tumor cells with little harm to normal cells. Yet, a single intervention strategy and poor …
[HTML][HTML] Hydrogen sulfide: from a toxic molecule to a key molecule of cell life
A Aroca, C Gotor, DC Bassham, LC Romero - Antioxidants, 2020 - mdpi.com
Hydrogen sulfide (H2S) has always been considered toxic, but a huge number of articles
published more recently showed the beneficial biochemical properties of its endogenous …
published more recently showed the beneficial biochemical properties of its endogenous …