Exogenous hydrogen sulfide donor NaHS alleviates nickel-induced epithelial-mesenchymal transition and the migration of A549 cells by regulating TGF-β1/Smad2 …

M Ye, M Yu, D Yang, J Li, H Wang, F Chen, H Yu… - Ecotoxicology and …, 2020 - Elsevier
Nickel compounds are known to be common environmental and occupational carcinogens
which also promote the migration of lung cancer cells. However, the molecular mechanism …

Increased nicotinamide phosphoribosyltransferase and cystathionine-β-synthase in renal oncocytomas, renal urothelial carcinoma, and renal clear cell carcinoma

RE Shackelford, J Abdulsattar, EX Wei… - Anticancer …, 2017 - ar.iiarjournals.org
Background: Renal oncocytomas (ROs), and clear cell (RCC) and urothelial carcinomas
(UC), are common renal neoplasms. Nicotinamide phosphoribosyltransferase (Nampt) …

ADT-OH, a hydrogen sulfide-releasing donor, induces apoptosis and inhibits the development of melanoma in vivo by upregulating FADD

F Cai, H Xu, N Cao, X Zhang, J Liu, Y Lu, J Chen… - Cell death & …, 2020 - nature.com
Hydrogen sulfide (H2S) is now widely considered the third endogenous gasotransmitter and
plays critical roles in cancer biological processes. In this study, we demonstrate that 5-(4 …

[HTML][HTML] S-nitrosothiols and H2S donors: Potential chemo-therapeutic agents in cancer

AKCA Reis, A Stern, HP Monteiro - Redox Biology, 2019 - Elsevier
Abstract Nitric Oxide (NO) and Hydrogen Sulfide (H 2 S) are components of an
“interactome”, which is defined as a redox system involving the interactions of RSS, RNS …

[HTML][HTML] Hymecromone naphthoquinone ethers as probes for hydrogen sulfide detection

D Słowiński, M Świerczyńska, A Grzelakowska… - Dyes and …, 2021 - Elsevier
Abstract Hydrogen sulfide (H 2 S), as one of the important gasotransmitters, plays an
essential role in a many physiological and pathological processes. Commonly used …

A julolidine-fused coumarin-NBD dyad for highly selective and sensitive detection of H2S in biological samples

I Ismail, D Wang, Z Wang, D Wang, C Zhang, L Yi… - Dyes and Pigments, 2019 - Elsevier
A new julolidine-fused coumarin-NBD probe 2 for H 2 S detection is rationally designed
based on the DFT caculations. This improved probe exhibits faster and larger off-on …

HA-ADT suppresses esophageal squamous cell carcinoma progression via apoptosis promotion and autophagy inhibition

SF Duan, MM Zhang, X Zhang, W Liu, SH Zhang… - Experimental Cell …, 2022 - Elsevier
Esophageal squamous cell carcinoma (ESCC) is a major cause of cancer-related deaths.
We have previously connected a non-sulfated glycosaminoglycan, hyaluronic acid (HA) …

[PDF][PDF] Treadmill exercise increases cystathionine γlyase expression and decreases inflammation in skeletal muscles of high-fat diet-induced obese rats

D Wu, Z Lu, M Li, Z Feng, A Liu, D Jin, A Ji, Y Li - Int J Clin Exp Med, 2016 - e-century.us
Obesity is a worldwide metabolic disorder that increases the risk of a number of human
diseases. Physical exercise has many beneficial effects on obesity and related disorders …

Hydrogen sulfide-activatable prodrug-backboned block copolymer micelles for delivery of chemotherapeutics

J Xiang, P Xing, X Liu, P Shen, S Shao, Q Zhou… - Polymer …, 2021 - pubs.rsc.org
Amphiphilic block copolymer prodrugs, which can self-assemble into stable core–shell
micelles, have been widely used for anticancer drug delivery. However, a major challenge is …

Exogenous hydrogen sulfide inhibits human melanoma cell development via suppression of the PI3K/AKT/mTOR pathway

Q Xiao, J Ying, Z Qiao, Y Yang, X Dai, Z Xu… - Journal of …, 2020 - Elsevier
Background: Melanoma is one of the most aggressive, therapy-resistant skin cancers in the
world. Hydrogen sulfide (H 2 S), a newly discovered gasotransmitter, plays a crucial role in …