Angiogenesis, the sprouting of new blood vessels from existing vessels, is one of six known
mechanisms employed by solid tumors to recruit blood vessels necessary for their initiation …

Integrins are adhesion receptors that allow cells to sense and respond to
microenvironmental signals encoded by the extracellular matrix. They are crucial for the …

MALAT1 has previously been described as a metastasis-promoting long noncoding RNA
(lncRNA). We show here, however, that targeted inactivation of the Malat1 gene in a …

A decline in capillary density and blood flow with age is a major cause of mortality and
morbidity. Understanding why this occurs is key to future gains in human health. NAD …

Significance: Regulation of cell adhesions during tissue repair is fundamentally important for
cell migration, proliferation, and protein production. All cells interact with extracellular matrix …

Neovascular age-related macular degeneration (exudative or wet AMD) is a prevalent,
progressive retinal degenerative macular disease that is characterized by …

Angiogenesis, the process of formation of new blood vessel from pre-existing ones, is
involved in various intertwined pathological processes including virus infection …

The main role of platelets is to control bleeding and repair vascular damage via thrombosis.
They have also been implicated to promote tumor metastasis through platelet-tumor cell …

Integrins belong to a large family of αβ heterodimeric transmembrane proteins first
recognized as adhesion molecules that bind to dedicated elements of the extracellular …

Clustering of cell membrane receptors regulates cell behaviors. Although receptor clustering
plans have achieved wide applications in cancer therapy, it still remains challenging to …