Osteoporosis, a disease characterized by low bone mass and alterations of bone
microarchitecture, leading to an increased risk for fragility fractures and, eventually, to …

Importance Down syndrome is the most common chromosomal condition, and average life
expectancy has increased substantially, from 25 years in 1983 to 60 years in 2020. Despite …

Given the progressive ageing of Western populations, the fragility fractures market has a
growing socioeconomic impact. Fragility fractures are common in the elderly, negatively …

Osteoporosis is defined as a skeletal disorder of compromised bone strength predisposing
those affected to an elevated risk of fracture. However, based on bone histology …

Vertebral fractures are independent risk factors for vertebral and nonvertebral fractures.
Since vertebral fractures are often missed, the relatively new introduction of vertebral …

Patients living with osteoporosis are projected to increase dramatically in the next decade.
Alongside the forecasted increased societal and economic burden, we will live a crisis of …

The fracture risk assessment tool, FRAX®, was released in 2008 and provides country-
specific algorithms for estimating individualized 10-year probability of hip and major …

Purpose Given the current life expectancy and number of individuals living with Down
syndrome (DS), it is important to learn common occurrences of disease conditions across …

Background Since image-based fracture prediction models using deep learning are lacking,
we aimed to develop an X-ray-based fracture prediction model using deep learning with …

The introduction of the FRAX algorithms has facilitated the assessment of fracture risk on the
basis of fracture probability. FRAX integrates the influence of several well-validated risk …