Molecular drilling to combat salmonella typhi biofilm using L-Asparaginase via multiple targeting process

A Upadhyay, D Pal, A Kumar - Expert Opinion on Therapeutic …, 2024 - Taylor & Francis
ABSTRACT Objectives Salmonella Typhi biofilm condition is showing as a major public
health problem due to the development of antibiotic resistance and less available druggable …

Exploring and targeting potential druggable antimicrobial resistance targets ArgS, SecY, and MurA in Staphylococcus sciuri with TCM inhibitors through a subtractive …

A Khan, S Sohail, S Yaseen, S Fatima, A Wisal… - Functional & Integrative …, 2023 - Springer
Staphylococcus sciuri (also currently Mammaliicoccus sciuri) are anaerobic facultative and
non-motile bacteria that cause significant human pathogenesis such as endocarditis, wound …

Exploring Nocardia's ecological spectrum and novel therapeutic frontiers through whole-genome sequencing: unraveling drug resistance and virulence factors

S Nathar, R Rajmichael, C Jeyaraj Pandian… - Archives of …, 2024 - Springer
Nocardia farcinica is the leading pathogen responsible for nocardiosis, a life-threatening
infection primarily affecting immunocompromised patients. In this study, the genomic …

Functional network analysis identifies multiple virulence and antibiotic resistance targets in Stenotrophomonas maltophilia

L Pinto, RP Shastry, S Alva, RSP Rao, SD Ghate - Microbial Pathogenesis, 2023 - Elsevier
Stenotrophomonas maltophilia, an emerging multidrug-resistant opportunistic bacterium in
humans is of major concern for immunocompromised individuals for causing pneumonia …

Bridging drug discovery through hierarchical subtractive genomics against asd, trpG, and secY of pneumonia causing MDR Staphylococcus aureus

A Wisal, N Saeed, M Aurongzeb, M Shafique… - Molecular Genetics and …, 2024 - Springer
Staphylococcus aureus (S. aureus) is an opportunistic gram-positive, non-motile, and non-
sporulating bacteria that induces pneumonia, a provocative lung infection affecting mainly …