The gut microbiome and the intestinal immune system are driving contributors to
inflammatory bowel diseases (IBD). Both have an important signalling factor in common …

Inflammatory bowel disease (IBD) is a complex genetic disease that is instigated and
amplified by the confluence of multiple genetic and environmental variables that perturb the …

The vagus nerve is a mixed nerve, comprising 80% afferent fibers and 20% efferent fibers. It
allows a bidirectional communication between the central nervous system and the digestive …

Inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis, is an
inflammatory condition that results in gastrointestinal tract damage. Various factors …

Organoids can shed light on the dynamic interplay between complex tissues and rare cell
types within a controlled microenvironment. Here, we develop gut organoid cocultures with …

Nowadays, non-biological treatments remain valuable approaches among the therapeutic
armamentarium of inflammatory bowel disease (IBD). Mesalamine is the core treatment of …

Inflammatory bowel diseases (IBDs) are idiopathic gastrointestinal inflammatory disorders
featuring chronic intestinal inflammation. Although IBDs are increasingly becoming globally …

Ulcerative colitis (UC) is a chronic, relapsing inflammatory bowel disease that features
colonic epithelial barrier dysfunction and gut dysbiosis. Preclinical studies demonstrated that …

Inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis, is a
complex immune-mediated disease of the gastrointestinal tract that increases morbidity and …

BACKGROUND Sirtuin 1 (SIRT1) is a nicotinamide adenine dinucleotide (NAD+)-dependent
protein deacetylase that is involved in various diseases, including cancers, metabolic …