Asthma is chronic inflammation of the airways characterized by airway hyper-
responsiveness, wheezing, cough, and dyspnea. Asthma affects> 350 million people …

After 60 years of intense fundamental research into T cell-mediated cytotoxicity, we have
gained a detailed knowledge of the cells involved, specific recognition mechanisms and …

While detailed analysis of aberrant cancer cell signaling pathways and changes in cancer
cell DNA has dominated the field of breast cancer biology for years, there now exists …

Immunotherapy based on checkpoint inhibitors is providing substantial clinical benefit, but
only to a minority of cancer patients. The current priority is to understand why the majority of …

Placenta-derived mesenchymal stromal cells (MSC) have attracted more attention for their
immune modulatory properties and poor immunogenicity, which makes them suitable for …

Essential hypertension (EH) is a complex, polygenic condition with no single causative
agent. Despite advances in our understanding of the pathophysiology of EH, hypertension …

Lung cancer (LC) is one of the leading causes of cancer occurrence and mortality
worldwide. Treatment of patients with advanced and metastatic LC presents a significant …

Disclosures: S. Fuchs reported being an employee of F. Hoffmann-La Roche (Roche) AG.
FG Kapp reported personal fees from Novartis outside the submitted work. MG Seidel …

Background. Apoptosis contributes to the severity of ischemia-reperfusion injury (IRI),
limiting the use of extended criteria donors in liver transplantation (LT). Machine perfusion …

Kalanchoe species are succulents with anti-inflammatory, antioxidant, and analgesic
properties, as well as cytotoxic activity. One of the most popular species cultivated in Europe …