Risk factors for vancomycin‐associated acute kidney injury: A systematic review and meta‐analysis

JY Kim, J Yee, HY Yoon, JM Han… - British Journal of …, 2022 - Wiley Online Library
Aims This systematic literature review and meta‐analysis aimed to evaluate the risk factors
for vancomycin‐associated acute kidney injury (AKI) incidence. Methods This study …

Vancomycin area under the curve versus trough only guided dosing and the risk of acute kidney injury: Systematic review and meta‐analysis

E Abdelmessih, N Patel, J Vekaria… - … : The Journal of …, 2022 - Wiley Online Library
Vancomycin is commonly used to treat methicillin‐resistant Staphylococcus aureus
infections and is known to cause nephrotoxicity. Previous Vancomycin Consensus …

Area-Under-Curve–Guided Versus Trough-Guided Monitoring of Vancomycin and Its Impact on Nephrotoxicity: A Systematic Review and Meta-Analysis

AS Lim, SHW Foo, JJB Seng, TTM Ng… - Therapeutic Drug …, 2023 - journals.lww.com
Background: Conventionally, vancomycin trough levels have been used for therapeutic drug
monitoring (TDM). Owing to the increasing evidence of trough levels being poor surrogates …

A monocentric retrospective study of AUC/MIC ratio of vancomycin associated with clinical outcomes and nephrotoxicity in patients with enterococcal infections

W Katip, P Oberdorfer - Pharmaceutics, 2021 - mdpi.com
Vancomycin is an antibiotic commonly used for the treatment of enterococcal infections.
However, there is no clear correlation regarding of vancomycin area under the …

Nephrotoxicity of vancomycin in combination with beta-lactam agents: ceftolozane-tazobactam vs piperacillin-tazobactam

S Alosaimy, AM Lagnf, ALV Hobbs… - Clinical Infectious …, 2023 - academic.oup.com
Background Vancomycin (VAN)-associated acute kidney injury (AKI) is increased when VAN
is combined with certain beta-lactams (BLs) such as piperacillin-tazobactam (TZP) but has …

Understanding vancomycin nephrotoxicity augmented by β-lactams: a synthesis of endosymbiosis, proximal renal tubule mitochondrial metabolism, and β-lactam …

S Alosaimy, MJ Rybak, G Sakoulas - The Lancet Infectious Diseases, 2023 - thelancet.com
The recent understanding that hydrophobic β-lactams have greater affinity for organic anion
transporter-3 (OAT-3) of the proximal renal tubule could provide valuable insights for …

Retrospective cohort study of the incidence of acute kidney injury with vancomycin area under the curve-based dosing with concomitant piperacillin-tazobactam …

PS Kiley, AP Pearston, LA Hodge… - Antimicrobial Agents …, 2022 - Am Soc Microbiol
Acute kidney injury (AKI) is a complication associated with vancomycin. Previous studies
demonstrated that the combination of vancomycin and piperacillin-tazobactam increases the …

Vancomycin associated acute kidney injury in patients with infectious endocarditis: a large retrospective cohort study

P Kunming, H Ying, X Chenqi, C Zhangzhang… - Frontiers in …, 2023 - frontiersin.org
Background: Vancomycin remains the cornerstone antibiotic for the treatment of infective
endocarditis (IE). Vancomycin has been associated with significant nephrotoxicity. However …

Pharmacokinetic assessment of vancomycin in critically ill patients and nephrotoxicity prediction using individualized pharmacokinetic parameters

P Ghasemiyeh, A Vazin, F Zand, E Haem… - Frontiers in …, 2022 - frontiersin.org
Introduction: Therapeutic drug monitoring (TDM) and pharmacokinetic assessments of
vancomycin would be essential to avoid vancomycin-associated nephrotoxicity and obtain …

Evaluating the Nephrotoxicity of Area-under-the-Curve-Based Dosing of Vancomycin with Concomitant Antipseudomonal Beta-Lactam Antibiotics: A Systematic …

CY Chiu, A Sarwal - Medicina, 2023 - mdpi.com
Background and Objectives: Vancomycin combined with piperacillin/tazobactam
(vancomycin+ piperacillin/tazobactam) has a higher risk of acute kidney injury (AKI) than …