Secretory proteins are exported from the endoplasmic reticulum (ER) at specialized regions
known as the transitional ER (tER). Coat protein complex II (COPII) proteins are enriched at …

Exit of cargo molecules from the endoplasmic reticulum (ER) for transport to the Golgi is the
initial step in intracellular vesicular trafficking. The coat protein complex II (COPII) machinery …

The Golgi apparatus plays essential roles in intracellular trafficking, protein and lipid
modification, and polysaccharide synthesis in eukaryotic cells. It is well known for its unique …

Cellular life depends on protein transport and membrane traffic. In multicellular organisms,
membrane traffic is required for extracellular matrix deposition, cell adhesion, growth factor …

Plant cells face unique challenges to efficiently export cargo from the endoplasmic reticulum
(ER) to mobile Golgi stacks. Coat protein complex II (COPII) components, which include two …

The coat protein complex II (COPII) mediates forward trafficking of protein and lipid cargoes
from the endoplasmic reticulum. COPII is an ancient and essential pathway in all eukaryotes …

Abstract RNase H1-dependent, phosphorothioate-modified antisense oligonucleotides (PS-
ASOs) can enter cells through endocytic pathways and need to be released from the …

CFTR is a transmembrane protein that reaches the cell surface via the conventional Golgi
mediated secretion pathway. Interestingly, ER-to-Golgi blockade or ER stress induces …

Recurrent miscarriage (RM) and unexplained infertility (UI) are gordian knots in reproductive
medicine, which are troubling many patients, doctors, and researchers. Although these two …

Cargo proteins exported from the endoplasmic reticulum to the Golgi apparatus are typically
transported in coat protein complex II (COPII)-coated vesicles of 60–90 nm diameter …