Genetic coding variants in APOL1, which encodes apolipoprotein L1 (APOL1), were
identified in 2010 and are relatively common among individuals of sub-Saharan African …

The lack of representation of diverse ancestral backgrounds in genomic research is well-
known, and the resultant scientific and ethical limitations are becoming increasingly …

Genetic variants in the APOL1 gene, found only in individuals of recent African ancestry,
greatly increase risk of multiple types of kidney disease. These APOL1 kidney risk alleles …

African trypanosomes are vector-borne protozoa, which cause significant human and animal
disease across sub-Saharan Africa, and animal disease across Asia and South America. In …

Progress has been made in the control or elimination of tropical diseases, with a significant
reduction of incidence. However, there is a risk of re-emergence if the factors fueling …

Background Genetic variants in apolipoprotein L1 (APOL1), a protein that protects humans
from infection with African trypanosomes, explain a substantial proportion of the excess risk …

Abstract Background Sub-Saharan Africans exhibit a higher frequency of chronic kidney
disease (CKD) than other populations. In this study, we sought to determine the frequency of …

African trypanosomes are extracellular flagellated unicellular protozoan parasites
transmitted by tsetse flies and causing Sleeping Sickness disease in humans and Nagana …

Little attention has been devoted to the role of HLA‐G gene and molecule on parasitic
disorders, and the available studies have focused on malaria, African and American …

Developing a complex collaborative program across multiple African countries,
characterized by a diversity of government models, laws, cultures and norms, resources and …