Global burden of liver disease: 2023 update

H Devarbhavi, SK Asrani, JP Arab, YA Nartey… - Journal of …, 2023 - Elsevier
Liver disease accounts for two million deaths annually and is responsible for 4% of all
deaths (1 out of every 25 deaths worldwide); approximately two-thirds of all liver-related …

[HTML][HTML] Liver transplantation as a cornerstone treatment for acute-on-chronic liver failure

MS Schulz, W Gu, AA Schnitzbauer… - Transplant …, 2022 - frontierspartnerships.org
Acute-on-chronic liver failure (ACLF) is a distinct clinical syndrome, characterized by acute
decompensation (AD) of liver cirrhosis, severe systemic inflammation, intra-and extrahepatic …

EASL Clinical Practice Guidelines on acute-on-chronic liver failure

R Moreau, M Tonon, A Krag, P Angeli, M Berenguer… - Journal of …, 2023 - Elsevier
Acute-on-chronic liver failure (ACLF), which was described relatively recently (2013), is a
severe form of acutely decompensated cirrhosis characterised by the existence of organ …

Predicting the Onset of Hepatitis B Virus–Related Acute-on-Chronic Liver Failure

J Luo, X Liang, J Xin, J Li, P Li, Q Zhou, S Hao… - Clinical …, 2023 - Elsevier
Background & Aims Acute-on-chronic liver failure (ACLF) is a life-threatening syndrome with
rapid progression. This study aimed to develop and validate a prognostic score to predict the …

Sepsis-induced endothelial dysfunction drives acute-on-chronic liver failure through Angiopoietin-2-HGF-C/EBPβ pathway

G Elias, M Schonfeld, S Saleh, M Parrish… - Hepatology, 2023 - journals.lww.com
Sepsis-induced endothelial dysfunction drives acute-on-chron... : Hepatology Sepsis-induced
endothelial dysfunction drives acute-on-chronic liver failure through Angiopoietin-2-HGF-C/EBPβ …

[HTML][HTML] Engineered human liver based on pullulan-dextran hydrogel promotes mice survival after liver failure

C Le Guilcher, G Merlen, A Dellaquila, MN Labour… - Materials Today Bio, 2023 - Elsevier
Liver tissue engineering approaches aim to support drug testing, assistance devices, or
transplantation. However, their suitability for clinical application remains unsatisfactory …

[HTML][HTML] Sarcopenia as a prognostic indicator of liver cirrhosis

SE Kim, DJ Kim - Journal of Cachexia, Sarcopenia and Muscle, 2022 - ncbi.nlm.nih.gov
Liver cirrhosis (LC) is widely prevalent and is associated with high mortality, accounting for
3.5% of all deaths worldwide. 1 Traditionally, LC is divided into compensated cirrhosis …

Acute-on-chronic liver failure in cirrhosis

C Gambino, S Piano, P Angeli - Journal of clinical medicine, 2021 - mdpi.com
Acute-on-chronic liver failure (ACLF) is a syndrome that develops in patients with acutely
decompensated chronic liver disease. It is characterised by high 28-day mortality, the …

Lessons on brain edema in HE: from cellular to animal models and clinical studies

K Pierzchala, A Hadjihambi, J Mosso, R Jalan… - Metabolic brain …, 2024 - Springer
Brain edema is considered as a common feature associated with hepatic encephalopathy
(HE). However, its central role as cause or consequence of HE and its implication in the …

Liver transplantation in Acute-on-Chronic liver failure: Timing of transplantation and selection of patient population

X Li, L Zhang, C Pu, S Tang - Frontiers in Medicine, 2022 - frontiersin.org
Acute-on-Chronic liver failure (ACLF) is a clinical syndrome with high short-term mortality.
Alcoholic ACLF is prevalent in European and American countries, while hepatitis B virus …