Research advances on anticancer activities of matrine and its derivatives: An updated overview

H ur Rashid, Y Xu, Y Muhammad, L Wang… - European journal of …, 2019 - Elsevier
Cancer is the second leading cause of mortality, only overcome by cardiovascular diseases,
and has caused more than 8.7 million deaths in 2015 all over the world. This figure is …

Anti-tumor activities of matrine and oxymatrine: literature review

Y Liu, Y Xu, W Ji, X Li, B Sun, Q Gao, C Su - Tumor Biology, 2014 - Springer
Matrine (MT) and oxymatrine (OMT), two kinds of alkaloid components found in the roots of
Sophora species, have various pharmacological activities and are demonstrated to have …

Research progress of natural Matrine compounds and synthetic Matrine derivatives

J Li, S Wei, D Marabada, Z Wang, Q Huang - Molecules, 2023 - mdpi.com
Matrine is a quinoline alkaloid extracted and separated from the dried root, fruit, and other
parts of the plant Sophora flavescens using an organic solvent. Matrine exhibits a variety of …

Quinolizidine alkaloids derivatives from Sophora alopecuroides Linn: Bioactivities, structure-activity relationships and preliminary molecular mechanisms

Y Li, G Wang, J Liu, L Ouyang - European Journal of Medicinal Chemistry, 2020 - Elsevier
Quinolizidine alkaloids, as essential active ingredients extracted from Sophora
alopecuroides Linn, have been well concerned in the past several decades owing to the …

Research advances on anti-cancer natural products

M Guo, J Jin, D Zhao, Z Rong, LQ Cao, AH Li… - Frontiers in …, 2022 - frontiersin.org
Malignant tumors seriously threaten people's health and life worldwide. Natural products,
with definite pharmacological effects and known chemical structures, present dual …

Matrine: Bioactivities and structural modifications

J Huang, H Xu - Current Topics in Medicinal Chemistry, 2016 - ingentaconnect.com
Matrine is a quinolizidine alkaloid isolated from the roots of Sophora flavescens (Kushen),
Sophora tonkinensis, and Sophora alopecuroides (Kudouzi). Matrine and its derivatives …

An Extra‐Large‐Pore Zeolite with 24× 8× 8‐Ring Channels Using a Structure‐Directing Agent Derived from Traditional Chinese Medicine

C Zhang, E Kapaca, J Li, Y Liu, X Yi… - Angewandte Chemie …, 2018 - Wiley Online Library
Extra‐large‐pore zeolites have attracted much interest because of their important
applications for processing larger molecules. Although great progress has been made in …

Synthesis of matrinic amide derivatives containing 1, 3, 4-thiadiazole scaffold as insecticidal/acaricidal agents

M Lv, G Liu, M Jia, H Xu - Bioorganic chemistry, 2018 - Elsevier
In continuation of our program aimed at the development of natural product-based pesticidal
agents, a series of matrinic amide derivatives containing 1, 3, 4-thiadiazole scaffold were …

Preparation of Matrinic/Oxymatrinic Amide Derivatives as Insecticidal/Acaricidal Agents and Study on the Mechanisms of Action against Tetranychus cinnabarinus

H Xu, M Xu, Z Sun, S Li - Journal of agricultural and food chemistry, 2019 - ACS Publications
In continuation of our program to develop natural-product-based pesticidal candidates,
matrinic/oxymatrinic amides were obtained through structural optimization of matrine. N′-(4 …

Antiviral effect of matrine against human enterovirus 71

Y Yang, J Xiu, X Zhang, L Zhang, K Yan, C Qin, J Liu - Molecules, 2012 - mdpi.com
Human enterovirus 71, a member of the Picornaviridae family, is one of the major causative
agent of hand, foot and mouth disease in children less than six years old. This illness has …