Analysis of the interactive effects of combinations of hormones or other manipulations with
qualitatively similar individual effects is an important topic in basic and clinical …

The role of glucagon-like peptide 1 (GLP-1) in insulin-dependent signaling is well-known;
GLP-1 enhances glucose-dependent insulin secretion and lowers blood glucose in …

Due to the limited efficacy of existing medications for addictive disorders including alcohol
use disorder (AUD), the need for additional medications is substantial. Potential new …

Although the gut and brain are separate organs, they communicate with each other via
trillions of intestinal bacteria that collectively make up one's gut microbiome. Findings from …

This paper is the thirty-sixth consecutive installment of the annual review of research
concerning the endogenous opioid system. It summarizes papers published during 2013 …

Rationale Opioid antagonism reduces the consumption of palatable foods in humans but the
neural substrates implicated in these effects are less well understood. Objectives The aim of …

Repeated administration of the long-acting glucagon-like peptide 1 receptor agonist exendin-
4 (EX-4) has been shown to reduce food intake and body weight and do so without a …

Aim To investigate the changes of circulating levels of all proglucagon‐derived peptides
(PGDPs) in individuals with overweight or obesity receiving liraglutide (3 mg) or …

摘要背景: 除了具有葡萄糖调节作用之外, 唾液素‐4, 一种稳定的胰升糖素样肽‐1 受体激动剂,
还具有胰腺保护作用与减肥作用. 为了使这些额外的疗效最佳化, 适当地联合使用其他的减肥 …

The poly (ethylene glycol)-b-brush poly (l-lysine) polymer (PEG-b-(PELG50-g-PLL3)) was
synthesized and evaluated as a nanocarrier for prolonging delivery of exenatide through the …