Background Liposomal bupivacaine is purported to extend analgesia of peripheral nerve
blocks when administered perineurally. However, evidence of the clinical effectiveness of …

In this narrative review article, the authors discuss the anatomy, nomenclature, history,
approaches (posterior vs. lateral vs. subcostal), techniques, pharmacology, indications, and …

The authors provide a comprehensive summary of all randomized, controlled trials (n= 76)
involving the clinical administration of liposomal bupivacaine (Exparel; Pacira …

Background Enhanced recovery after surgery (ERAS) pathways have been shown to
considerably reduce complications, length of stay and costs after most of surgical …

Local anesthetics are the only class of drugs that can fully block nociceptive impulses from
reaching the cerebral cortex and, thus, they represent the only means of completely …

Traditionally, pain relief for abdominal surgery has centred on epidural analgesia, but
transversus abdominis plane block is increasingly being used. Our aim was to compare the …

Objective Compare transversus abdominis plane (TAP) blocks with liposomal bupivacaine
were to epidural analgesia for pain at rest and opioid consumption in patients recovering …

Extended-release local anesthetics (LAs) have drawn increasing attention with their
promising role in improving analgesia and reducing adverse events of LAs. Nano-structured …

Background The efficacy of transversus abdominis plane (TAP) block compared with
thoracic epidural analgesia (TEA) in abdominal surgery has been controversial. We …

Background The opioid crisis has prompted surgeons to search for alternative postoperative
methods of analgesia. Liposomal bupivacaine is a long-acting local anesthetic formulation …