[HTML][HTML] Therapeutic potential of phenolic compounds in medicinal plants—Natural health products for human health

W Sun, MH Shahrajabian - Molecules, 2023 - mdpi.com
Phenolic compounds and flavonoids are potential substitutes for bioactive agents in
pharmaceutical and medicinal sections to promote human health and prevent and cure …

[HTML][HTML] Natural product-based pharmacological studies for neurological disorders

V Puri, N Kanojia, A Sharma, K Huanbutta… - Frontiers in …, 2022 - frontiersin.org
Central nervous system (CNS) disorders and diseases are expected to rise sharply in the
coming years, partly because of the world's aging population. Medicines for the treatment of …

Destruction of the cellular antioxidant pool contributes to resveratrol‐induced senescence and apoptosis in lung cancer

C Liang, K Yi, X Zhou, X Li, C Zhong… - Phytotherapy …, 2023 - Wiley Online Library
Resveratrol (RES) has various pharmacological bioactivities and its anticancer effects in
lung cancer have been proven. However, the underlying mechanisms of action of RES in …

Nature's Toolbox Against Tau Aggregation: An Updated Review of Current Research

S Khan, MI Hassan, M Shahid, A Islam - Ageing Research Reviews, 2023 - Elsevier
Tau aggregation is a hallmark of several neurodegenerative disorders, such as Alzheimer's
disease (AD), frontotemporal dementia, and progressive supranuclear palsy …

[HTML][HTML] Aluminum exposure induces central nervous system impairment via activating NLRP3-medicated pyroptosis pathway

W Hao, X Zhu, Z Liu, Y Song, S Wu, X Lu, J Yang… - Ecotoxicology and …, 2023 - Elsevier
Purpose Aluminum is an environmental toxicant whose long-term exposure is closely
associated with nervous system impairment. This study mainly investigated neurological …

[HTML][HTML] Resveratrol analogues as dual inhibitors of monoamine oxidase b and carbonic anhydrase vii: a new multi-target combination for neurodegenerative …

S Carradori, M Fantacuzzi, A Ammazzalorso, A Angeli… - Molecules, 2022 - mdpi.com
Neurodegenerative diseases (NDs) are described as multifactorial and progressive
syndromes with compromised cognitive and behavioral functions. The multi-target-directed …

[HTML][HTML] Conjugation, prodrug, and co-administration strategies in support of nanotechnologies to improve the therapeutic efficacy of phytochemicals in the central …

G Rassu, M Sorrenti, L Catenacci, B Pavan, L Ferraro… - Pharmaceutics, 2023 - mdpi.com
Phytochemicals, produced as secondary plant metabolites, have shown interesting potential
therapeutic activities against neurodegenerative diseases and cancer. Unfortunately, poor …

Therapeutic potential of stilbenes in neuropsychiatric and neurological disorders: A comprehensive review of preclinical and clinical evidence

K Socała, E Żmudzka, K Lustyk, M Zagaja… - Phytotherapy …, 2024 - Wiley Online Library
Neuropsychiatric disorders are anticipated to be a leading health concern in the near future,
emphasizing an outstanding need for the development of new effective therapeutics to treat …

[HTML][HTML] Oligomeropathies, inflammation and prion protein binding

G Forloni, P La Vitola, C Balducci - Frontiers in Neuroscience, 2022 - frontiersin.org
The central role of oligomers, small soluble aggregates of misfolded proteins, in the
pathogenesis of neurodegenerative disorders is recognized in numerous experimental …

Resveratrol and Sir2 reverse sleep and memory defects induced by amyloid precursor protein

Y Hao, L Shao, J Hou, Y Zhang, Y Ma, J Liu, C Xu… - Neuroscience …, 2023 - Springer
Resveratrol (RES), a natural polyphenolic phytochemical, has been suggested as a putative
anti-aging molecule for the prevention and treatment of Alzheimer's disease (AD) by the …