MRI in multiple sclerosis: current status and future prospects

R Bakshi, AJ Thompson, MA Rocca, D Pelletier… - The Lancet …, 2008 - thelancet.com
Many promising MRI approaches for research or clinical management of multiple sclerosis
(MS) have recently emerged, or are under development or refinement. Advanced MRI …

[HTML][HTML] Overlapping neuroimmune mechanisms and therapeutic targets in neurodegenerative disorders

F De Marchi, I Munitic, L Vidatic, E Papić, V Rački… - Biomedicines, 2023 - mdpi.com
Many potential immune therapeutic targets are similarly affected in adult-onset
neurodegenerative diseases, such as Alzheimer's (AD) disease, Parkinson's disease (PD) …

Recent advances towards overcoming the blood–brain barrier

A Ali, MS Arshad, MA Khan, MW Chang, Z Ahmad - Drug Discovery Today, 2023 - Elsevier
The blood–brain barrier (BBB) is a protective element of the neurovascular unit (NVU)
surrounded by astrocytes, pericytes, extracellular matrix, and the tight junctional complex …

[HTML][HTML] The effect of probiotic supplementation on the clinical and Para-clinical findings of multiple sclerosis: a randomized clinical trial

KM Asghari, N Dolatkhah, H Ayromlou, F Mirnasiri… - Scientific Reports, 2023 - nature.com
Multiple Sclerosis (MS) is a chronic demyelination disease of the central nervous system
(CNS). The gut-brain axis involves communication between the nervous, endocrine, and …

[HTML][HTML] The effects of dietary interventions on brain aging and neurological diseases

F Lobo, J Haase, S Brandhorst - Nutrients, 2022 - mdpi.com
Dietary interventions can ameliorate age-related neurological decline. Decades of research
of in vitro studies, animal models, and clinical trials support their ability and efficacy to …

The role of neuroinflammation in neurodegenerative diseases: current understanding and future therapeutic targets

A Adamu, S Li, F Gao, G Xue - Frontiers in Aging Neuroscience, 2024 - frontiersin.org
Neuroinflammation refers to a highly complicated reaction of the central nervous system
(CNS) to certain stimuli such as trauma, infection, and neurodegenerative diseases. This is a …

Antimicrobial, anticancer, antidiabetic, antineurodegenerative, and antirheumatic activities of thymol: clarification of mechanisms

QHA Aljelehawy, S Mohammadi… - Micro Nano Bio …, 2023 - mnba-journal.com
Thymol is monoterpenic phenol with a wide range of therapeutic properties. Various
pharmacological properties including antimicrobial, antineoplastic, anti-inflammatory …

Role of ketogenic diet in neurodegenerative diseases focusing on Alzheimer diseases: The guardian angle

HM Al-Kuraishy, MS Jabir, AK Albuhadily… - Ageing Research …, 2024 - Elsevier
The ketogenic diet (KD) is a low-carbohydrate, adequate protein and high-fat diet. KD is
primarily used to treat refractory epilepsy. KD was shown to be effective in treating different …

[HTML][HTML] Interaction of the gut microbiome and immunity in multiple sclerosis: impact of diet and immune therapy

SK Yadav, K Ito, S Dhib-Jalbut - International journal of molecular …, 2023 - mdpi.com
The bidirectional communication between the gut and central nervous system (CNS)
through microbiota is known as the microbiota–gut–brain axis. The brain, through the enteric …

[HTML][HTML] Recent advances and new perspectives in mitochondrial dysfunction

C Giulivi, K Zhang, H Arakawa - Scientific Reports, 2023 - nature.com
In the last decade, there has been an increased appreciation for mitochondria as central
hubs in diverse processes, such as cellular energy, immunity, and signal transduction. As …