The neurobiology of tumors has attracted considerable interest from clinicians and scientists
and has become a multidisciplinary area of research. Neural components not only interact …

The nervous and immune systems are the primary sensory interfaces of the body, allowing it
to recognize, process, and respond to various stimuli from both the external and internal …

Starvation therapy is an innovative approach in cancer treatment aimed at depriving cancer
cells of necessary resources by impeding tumor angiogenesis or blocking the energy …

Perineural invasion is a prevalent pathological finding in head and neck squamous cell
carcinoma and a risk factor for unfavorable survival. An adequate diagnosis of perineural …

During tumor development, the tumor itself must continuously generate new blood vessels to
meet their growth needs while also allowing for tumor invasion and metastasis. One of the …

Recent studies have highlighted neurons and their associated Schwann cells (SCs) as key
regulators of cancer development. However, the mode of their interaction with tumor cells or …

Pancreatic ductal adenocarcinoma (PDAC) is an aggressive malignant tumor with a high
metastatic potential. Perineural invasion (PNI) occurs in the early stages of PDAC with a …

Background and objectives Perineural invasion (PNI) refers to the invasion, encasement, or
penetration of tumor cells around or through nerves. Various malignant tumors, including …

Purpose We tested whether the PARP inhibitor, Olaparib, can effectively enhance
radiosensitivity while inhibiting OSCC growth and metastasis in vitro and in vivo. Patient …