Ever since natural sex hormones have been identified, their structure defined and their
synthesis achieved, it became clear that their circulating half-life was too short to allow use …

The release of steroids from Silastic R capsules and rods has been measured in human
beings and rats by recovering the implants after periods of subdermal implantation and …

A contraceptive vaginal ring containing levonorgestrel and estradiol was designed in which
the drug is located in a 0.15-mm layer beneath a 0.25-mm overcoat at the ring's surface …

This paper presents results of a double blind, multi-centered and multi-national study of two
progestin only subdermal implants used for contraception. A regimen of six capsules of …

The metabolism of the synthetic progestin,[3H] medroxyprogesterone acetate (MPA), was
studied in women using a single injection technique. Computer-implemented analysis was …

The effects of a combination of a progestin, levonorgestrel (LNg), and estrone (E1), on
exocrine and endocrine testicular function were examined in adult men. The mode of …

The levels of levonorgestrel (L-NOG), progesterone and estradiol were measured in plasma
samples of 17 normally menstruating women during a control cycle and during a …

Dimethyl-polysiloxane capsules containing pure progestagens were attached to Tatum's T
IUDs and tested in 594 fertile women for contraceptive performance. The control group was …

The mode of action of compressed pellets containing 85 per cent norethindrone (NET) and
15 per cent cholesterol was studied. Four pellets were inserted subcutaneously, in each of …

Oral contraceptives have been implicated in causing flares of systemic lupus erythematosus
in humans, and studies of these agents in the NZB/W mouse model of lupus may help to …