The desmosome-keratin scaffold integrates ErbB family and mechanical signaling to polarize epidermal structure and function
KJ Green, CM Niessen, M Rübsam… - Frontiers in Cell and …, 2022 - frontiersin.org
While classic cadherin-actin connections in adherens junctions (AJs) have ancient origins,
intermediate filament (IF) linkages with desmosomal cadherins arose in vertebrate …
intermediate filament (IF) linkages with desmosomal cadherins arose in vertebrate …
Cutaneous dysbiosis may amplify barrier dysfunction in patients with atopic dermatitis
M Hammond, A Gamal, PK Mukherjee… - Frontiers in …, 2022 - frontiersin.org
Atopic dermatitis (AD) is associated with cutaneous dysbiosis, barrier defects, and immune
dysregulation, but the interplay between these factors needs further study. Early-onset …
dysregulation, but the interplay between these factors needs further study. Early-onset …
Mechanisms for initiation of food allergy by skin pre‐disposed to atopic dermatitis
H Gao, AE Kosins, JM Cook‐Mills - Immunological Reviews, 2024 - Wiley Online Library
Food allergy can be life‐threatening and often develops early in life. In infants and children,
loss‐of‐function mutations in skin barrier genes associate with food allergy. In a mouse …
loss‐of‐function mutations in skin barrier genes associate with food allergy. In a mouse …
Improvement of chronic kidney disease–associated pruritus after treatment with intravenous naloxone
MP Pereira, C Zeidler, S Ständer - JAMA dermatology, 2021 - jamanetwork.com
Improvement of Chronic Kidney Disease–Associated Pruritus After Treatment With Intravenous
Naloxone | Chronic Kidney Disease | JAMA Dermatology | JAMA Network [Skip to Navigation] …
Naloxone | Chronic Kidney Disease | JAMA Dermatology | JAMA Network [Skip to Navigation] …
A cell-based drug discovery assay identifies inhibition of cell stress responses as a new approach to treatment of epidermolysis bullosa simplex
TS Tan, JEA Common, JSY Lim… - Journal of Cell …, 2021 - journals.biologists.com
In the skin fragility disorder epidermolysis bullosa simplex (EBS), mutations in keratin 14
(K14, also known as KRT14) or keratin 5 (K5, also known as KRT5) lead to keratinocyte …
(K14, also known as KRT14) or keratin 5 (K5, also known as KRT5) lead to keratinocyte …
Prevalence and characterization of itch in pachyonychia congenita
Methods| The IPCRR is a global registry of individuals with genetically confirmed PC
(https://www. pachyonychia. org/patient-registry/). 1 All patients give written informed …
(https://www. pachyonychia. org/patient-registry/). 1 All patients give written informed …
Mechanisms for Alternaria alternata Function in the Skin During Induction of Peanut Allergy in Neonatal Mice With Skin Barrier Mutations
LM Buelow, A Hoji, K Tat, LM Schroeder-Carter… - Frontiers in …, 2021 - frontiersin.org
Neonatal mice with heterozygous mutations in genes encoding the skin barrier proteins
filaggrin and mattrin (flaky tail mice [FT+/−]) exhibit oral peanut-induced anaphylaxis after …
filaggrin and mattrin (flaky tail mice [FT+/−]) exhibit oral peanut-induced anaphylaxis after …
Epithelial barrier regulation, antigen sampling, and food allergy
JM Cook-Mills, LN Emmerson - Journal of Allergy and Clinical Immunology, 2022 - Elsevier
Food allergy is often associated with development of atopic dermatitis. Atopic dermatitis is a
chronic inflammatory skin condition with a strong association with skin barrier gene …
chronic inflammatory skin condition with a strong association with skin barrier gene …
[PDF][PDF] Analysis of the mechanism of Sophorae Flavescentis Radix in the treatment of intractable itching based on network pharmacology and molecular docking.
Y Xiao, RJ Wang, HK Zeng, J Xie… - European Review for …, 2023 - europeanreview.org
RESULTS: The SFR-components-targets-intractable itching Protein-Protein Interactions
(PPI) network was established, and 22 active components and 42 targets were screened …
(PPI) network was established, and 22 active components and 42 targets were screened …