Mesoporous silica nanoparticles: An emerging approach in overcoming the challenges with oral delivery of PPs

SR Pamshong, D Bhatane, S Sarnaik… - Colloids and Surfaces B …, 2023 - Elsevier
Proteins and peptides (PPs), as therapeutics are widely explored in the past few decades,
by virtue of their inherent advantages like high specificity and biocompatibility with minimal …

Current advances in modulating tumor hypoxia for enhanced therapeutic efficacy

Z Liu, X Liu, W Zhang, R Gao, H Wei, CY Yu - Acta Biomaterialia, 2024 - Elsevier
Hypoxia is a common feature of most solid tumors, which promotes the proliferation,
invasion, metastasis, and therapeutic resistance of tumors. Researchers have been …

A Molecular Switch‐Integrated Nanoplatform Enables Photo‐Unlocked Antibacterial Drug Delivery for Synergistic Abscess Therapy

Y Yan, Y Liu, J Li, Y Li, H Wu, H Li, X Ma… - Advanced …, 2023 - Wiley Online Library
Drug delivery systems (DDSs) capable of sequential multistage drug release are urgently
needed for antibacterial applications. Herein, a molecular switch‐integrated, photo …

Recent Developments in Nanoparticle Formulations for Resveratrol Encapsulation as an Anticancer Agent

M Ali, V Benfante, D Di Raimondo, G Salvaggio… - Pharmaceuticals, 2024 - mdpi.com
Resveratrol is a polyphenolic compound that has gained considerable attention in the past
decade due to its multifaceted therapeutic potential, including anti-inflammatory and …

Preparation of magnetic iron oxide incorporated mesoporous silica hybrid composites for ph and temperature-sensitive drug delivery

M Santhamoorthy, K Thirupathi, S Krishnan… - Magnetochemistry, 2023 - mdpi.com
In clinical applications for cancer treatment, chemotherapy coupled with thermotherapy is
highly considered. The development of multifunctional nanocomposite materials is an …

Tailoring drug delivery systems by microfluidics for tumor therapy

Q Zhang, G Kuang, L Wang, L Fan, Y Zhao - Materials Today, 2024 - Elsevier
Drug delivery systems (DDSs) for tumor treatment is a specialized method aimed at
transporting therapeutic substances, especially anticancer drugs, to specific target areas in …

Intracellularly Synthesized Artificial Exosome Treats Acute Lung Injury

L Liang, W Peng, A Qin, J Zhang, R Chen, D Zhou… - ACS …, 2024 - ACS Publications
Acute lung injury (ALI) and its severe form, acute respiratory distress syndrome (ARDS),
induce high morbidity and mortality rates, which challenge the present approaches for the …

Nanoporous silica nanoparticles coated with peptide P14 and decorated with 5-fluorouracil and indocyanine green for NIR-triggered photothermal/photodynamic …

P Song, G Xu, G Peng, L Gui, W Li, W Li… - ACS Applied Nano …, 2023 - ACS Publications
Nowadays, many cancer treatment paradigms are being rewritten due to advances in
materials science, nanotechnology, and biomedicine. With the aid of nanomaterials and …

Glutathione depletion based Pt (IV) hybrid mesoporous organosilica delivery system to conquer cisplatin chemoresistance: A “one stone three birds” strategy

L Ju, Z Huang, Q Shen, C Fu, S Li, W Duan, C Xu… - Chinese Chemical …, 2024 - Elsevier
The occurrence of acquired resistance to cisplatin (DDP) that induces the toxic drug effects
has always been a huge challenge and urgently needs to be resolved in the cancer …

Development of mesoporous silica-based nanoparticles for cancer phototherapy

B Sun, H Chen, Y Wang, X Wang, WHZ He, C Xie… - Dyes and …, 2023 - Elsevier
The mesoporous silica nanoparticles (MSNs)-based nanoplatform has garnered increasing
attention in the field of cancer phototherapy, owing to the unique characteristics of MSNs …