[HTML][HTML] Going below and beyond the surface: Microneedle structure, materials, drugs, fabrication, and applications for wound healing and tissue regeneration

S Lyu, Z Dong, X Xu, HP Bei, HY Yuen, CWJ Cheung… - Bioactive materials, 2023 - Elsevier
Microneedle, as a novel drug delivery system, has attracted widespread attention due to its
non-invasiveness, painless and simple administration, controllable drug delivery, and …

New insights into balancing wound healing and scarless skin repair

S Zhou, M Xie, J Su, B Cai, J Li… - Journal of Tissue …, 2023 - journals.sagepub.com
Scars caused by skin injuries after burns, wounds, abrasions and operations have serious
physical and psychological effects on patients. In recent years, the research of scar free …

[HTML][HTML] Scarless wound healing programmed by core-shell microneedles

Y Zhang, S Wang, Y Yang, S Zhao, J You… - Nature …, 2023 - nature.com
Effective reprogramming of chronic wound healing remains challenging due to the limited
drug delivery efficacy hindered by physiological barriers, as well as the inappropriate dosing …

Layered GelMA/PEGDA hydrogel microneedle patch as an intradermal delivery system for hypertrophic scar treatment

Z Chen, X Hu, Z Lin, H Mao, Z Qiu… - … Applied Materials & …, 2023 - ACS Publications
Hypertrophic scar (HS) is an unfavorable skin disorder that typically develops after trauma,
burn injury, or surgical procedures and causes numerous physical and psychological issues …

MiR‐141‐3p‐Functionalized Exosomes Loaded in Dissolvable Microneedle Arrays for Hypertrophic Scar Treatment

S Meng, Q Wei, S Chen, X Liu, S Cui, Q Huang, Z Chu… - Small, 2024 - Wiley Online Library
Hypertrophic scar (HS) is a common fibroproliferative disease caused by abnormal wound
healing after deep skin injury. However, the existing approaches have unsatisfactory …

[HTML][HTML] A tough, antibacterial and antioxidant hydrogel dressing accelerates wound healing and suppresses hypertrophic scar formation in infected wounds

X Liu, Y Sun, J Wang, Y Kang, Z Wang, W Cao, J Ye… - Bioactive Materials, 2024 - Elsevier
Wound management is an important issue that places enormous pressure on the physical
and mental health of patients, especially in cases of infection, where the increased …

Ferroptosis‐mediated synergistic therapy of hypertrophic scarring based on metal–organic framework microneedle patch

B Zhao, W Guo, X Zhou, Y Xue, T Wang… - Advanced Functional …, 2023 - Wiley Online Library
Hypertrophic scarring, an abnormal fibroproliferative wound‐healing disease, has brought
tremendous burden for global healthcare systems. To date, no satisfactory treatment of …

Magnetic Field‐Directed Deep Thermal Therapy via Double‐Layered Microneedle Patch for Promoting Tissue Regeneration in Infected Diabetic Skin Wounds

D He, X Liu, J Jia, B Peng, N Xu… - Advanced Functional …, 2024 - Wiley Online Library
Although near‐infrared (NIR) light‐based photothermal therapies have shown therapeutic
potential for infected wounds, the attenuation of NIR light intensity in tissue has severely …

Antimicrobial hydrogel microneedle loading verteporfin promotes skin regeneration by blocking mechanotransduction signaling

C Wei, C You, L Zhou, H Liu, S Zhou, X Wang… - Chemical Engineering …, 2023 - Elsevier
Excessive scar formation has severe physiological and psychological effects on patients,
and tissue restoration to functioning without scar generation after wounding continues to be …

Microneedles: a novel strategy for wound management

ZQ Zhao, L Liang, LY Jing, Y Liu, YH Zhang… - Biomaterials …, 2023 - pubs.rsc.org
Wound management is a serious concern worldwide, inflicting a huge social and economic
burden on patients and healthcare systems, and research into efficient wound-management …