A complex network of chemokines and their receptors influences the development of primary
tumours and metastases. New information about the biological role of chemokines in these …

Gallic acid, a predominant polyphenol, has been shown to inhibit carcinogenesis in animal
models and in vitro cancerous cell lines. The inhibitory effect of gallic acid on cancer cell …

The trafficking of circulating stem and progenitor cells to areas of tissue damage is poorly
understood. The chemokine stromal cell–derived factor-1 (SDF-1 or CXCL12) mediates …

Adult bone marrow (BM)‐derived stem cells, including hematopoietic stem cells (HSCs) and
MSCs, represent an important source of cells for the repair of a number of damaged tissues …

Adult neovascularization relies on the recruitment of circulating cells, but their angiogenic
roles and recruitment mechanisms are unclear. We show that the endothelial growth factor …

Malignant cells from at least 23 different types of cancer express the chemokine receptor
CXCR4 and respond to its ligand CXCL12. This receptor ligand pair appears to be involved …

Migration of hematopoietic stem cells through the blood, across the endothelial vasculature
to different organs and to their bone marrow (BM) niches, requires active navigation, a …

Studies of liver regenerative processes have gained new prominence, generated from
analyses of genetically engineered animal models, the transplantation of human livers, and …

Here we investigated the potential role of bone-resorbing osteoclasts in homeostasis and
stress-induced mobilization of hematopoietic progenitors. Different stress situations induced …

The importance of cancer stem cells (CSCs) in tumor-initiation has been firmly established in
leukemia and recently reported for a variety of solid tumors. However, the role of CSCs in …