PCSK9 inhibitors and cardiovascular outcomes

D Steffens, P Bramlage, C Scheeff… - Expert opinion on …, 2020 - Taylor & Francis
Introduction: Dyslipidemia, particularly elevated low-density lipoprotein cholesterol (LDL-C),
is a key risk factor for atherosclerotic cardiovascular disease (ASCVD), and lipid-lowering …

Pharmacokinetic drug evaluation of ezetimibe+ simvastatin for the treatment of hypercholesterolemia

M Bove, F Fogacci, AFG Cicero - Expert Opinion on Drug …, 2017 - Taylor & Francis
Introduction: Cholesterol lowering treatment is mainly based on statins eventually
associated to adjunctive drugs of different class such as ezetimibe. In the present review, we …

Antioxidant and hypolipidemic effects of soymilk fermented via Lactococcus acidophilus MF204

J Chen, Y Wu, C Yang, X Xu, Y Meng - Food & Function, 2017 - pubs.rsc.org
Previous studies have shown that fermentations can enhance the bioactivity and absorption
rate of soybean products. Fermented soybean products can alleviate hyperlipidemia and …

Pharmacokinetics, pharmacodynamics and clinical efficacy of non-statin treatments for hypercholesterolemia

AFG Cicero, M Bove, C Borghi - Expert Opinion on Drug …, 2018 - Taylor & Francis
Introduction: Hypercholesterolemia is the main modifiable risk factor for atherosclerosis
progression and cardiovascular disease (CVD) development. Its pharmacological …

[HTML][HTML] Role of pumpkin seed oil on some cardiovascular and renal aspects in adult male albino rats

BK Ramadan, SA Mohammad… - Al-Azhar Medical …, 2016 - journals.ekb.eg
Background: Obesity, a sort of dietary imbalance, is one of the most frequently encountered
medical problems associated with many complications as hypertension, hyperlipidemia, and …

Liver and Gastrointestinal Pharmacology

J Nguyen-Lee, CT Nguyen-Buckley… - … and Physiology for …, 2019 - Elsevier
One of the main functions of the liver is to protect the organism against intoxication. The
endoplasmic reticulum of liver cells contains enzymes that protect the organism against an …

Hypolipidemic Effects of Polysaccharides from Fermented Seaweed

Z Wang, Y Su, K Li, L Zhao, X Liu - IOP Conference Series …, 2019 - iopscience.iop.org
To study the hypolipidemic effect of a fermented seaweed polysaccharide on experimental
hyperlipidemic mice for Conducted a series of work. Algal polysaccharides can alleviate …

Neurocognitive performance after PCSK9 inhibitor therapy: Current state of the evidence.

CA Stamerra, P Di Giosia, P Giorgini… - Journal of …, 2017 - europepmc.org
Design and rationale of the EBBINGHAUS trial: A phase 3, double-blind, placebo-controlled,
multicenter study to assess the effect of evolocumab on cognitive function in patients with …

[PDF][PDF] Evolocumab in Combination with Statins for CVD Risk Reduction: An Evidential Review

RS Basutkar, T Tsundue, H Siva, R Durai… - Journal of …, 2018 - researchgate.net
Objectives: The objectives of this evidential review is to conceptualize the ability of
Evolocumab in combination with statins for reducing low density lipoprotein concentrations …

[HTML][HTML] Proprotein Convertase Subtilisin-Kexin Type 9 (PCSK9) Inhibitors and Cardiovascular Risk: Does a Further Analysis of the Fourier Trial Suggest Changes in …

N Cervelli, G Tocci, C Ferri - High Blood Pressure & Cardiovascular …, 2018 - Springer
Circulating LDL-cholesterol (LDL-C) concentration is a well established, modifiable risk
factor for atherosclerosis [1]. According to this, decrements in serum LDL-C levels are …