Microbiome-gut-brain axis and toll-like receptors in Parkinson's disease

V Caputi, MC Giron - International journal of molecular sciences, 2018 - mdpi.com
Parkinson's disease (PD) is a progressively debilitating neurodegenerative disease
characterized by α-synucleinopathy, which involves all districts of the brain-gut axis …

Beyond macromolecules: extracellular vesicles as regulators of inflammatory diseases

K Das, S Paul, T Mukherjee, A Ghosh, A Sharma… - Cells, 2023 - mdpi.com
Inflammation is the defense mechanism of the immune system against harmful stimuli such
as pathogens, toxic compounds, damaged cells, radiation, etc., and is characterized by …

Biochemical evaluation of the antioxidant effects of hydroxytyrosol on pancreatitis-associated gut injury

R Fusco, M Cordaro, R Siracusa, R D'Amico… - Antioxidants, 2020 - mdpi.com
Acute pancreatitis is a severe abdominal pathology often associated with several
complications including gut dysfunction. Oxidative stress is one of the most important …

Systemic inflammation response index and systemic immune inflammation index are associated with clinical outcomes in patients with acute pancreatitis?

M Biyik, Z Biyik, M Asil, M Keskin - Journal of Investigative Surgery, 2022 - Taylor & Francis
Objectives: The inflammatory response is critically important in acute pancreatitis (AP).
Systemic immune-inflammation (SII) index and systemic inflammation response index (SIRI) …

Hypoxia‐inducible factor‐1: A potential target to treat acute lung injury

Y Liu, D Xiang, H Zhang, H Yao… - Oxidative medicine and …, 2020 - Wiley Online Library
Acute lung injury (ALI) is an acute hypoxic respiratory insufficiency caused by various intra‐
and extrapulmonary injury factors. Presently, excessive inflammation in the lung and the …

NLRP3 inflammasome-mediated inflammation in acute pancreatitis

A Ferrero-Andrés, A Panisello-Roselló… - International Journal of …, 2020 - mdpi.com
The discovery of inflammasomes has enriched our knowledge in the pathogenesis of
multiple inflammatory diseases. The NLR pyrin domain-containing protein 3 (NLRP3) has …

Adipose saturation reduces lipotoxic systemic inflammation and explains the obesity paradox

B Khatua, B El-Kurdi, K Patel, C Rood, P Noel… - Science …, 2021 - science.org
Obesity sometimes seems protective in disease. This obesity paradox is predominantly
described in reports from the Western Hemisphere during acute illnesses. Since adipose …

The role of neutrophils and neutrophil extracellular traps in acute pancreatitis

J Wan, Y Ren, X Yang, X Li, L Xia, N Lu - Frontiers in Cell and …, 2021 - frontiersin.org
Leukocyte invasion (neutrophils and monocytes/macrophages) is closely related to the
severity of acute pancreatitis (AP) and plays an important role in the systemic inflammatory …

Pancreatitis aguda: evidencia actual

DB Durón, AG Laínez, WU García, LL Rubio… - Archivos de …, 2018 - dialnet.unirioja.es
La pancreatitis aguda es uno de los trastornos gastrointestinales más comunes que
requieren hospitalización. Las 3 causas principales en orden de importancia son los …

Role of Chemerin/ChemR23 axis as an emerging therapeutic perspective on obesity-related vascular dysfunction

Y Xie, L Liu - Journal of translational medicine, 2022 - Springer
Sufficient epidemiological investigations demonstrate that there is a close correlation
between obesity and vascular dysfunction. Nevertheless, specific mechanisms underlying …