Intranasal corticosteroids: topical potency, systemic activity and therapeutic index

PT Daley-Yates, D Larenas-Linnemann… - Journal of asthma …, 2021 - Taylor & Francis
Intranasal corticosteroid (INCS) therapy is the preferred treatment option for allergic rhinitis
(AR). Although all INCSs for the treatment of AR are considered safe and effective …

[HTML][HTML] TLR signals in epithelial cells in the nasal cavity and paranasal sinuses

M Suzuki, C Cooksley, T Suzuki, M Ramezanpour… - Frontiers in …, 2021 - frontiersin.org
The respiratory tract is constantly at risk of invasion by microorganisms such as bacteria,
viruses, and fungi. In particular, the mucosal epithelium of the nasal cavity and paranasal …

[HTML][HTML] Considerations for shared decision-making in treatment of chronic rhinosinusitis with nasal polyps

SP Ramkumar, D Lal, A Miglani - Frontiers in Allergy, 2023 - frontiersin.org
Shared decision-making is an approach where physicians and patients work together to
determine a personalized treatment course. Such an approach is integral to patient-centered …

Adverse drug reactions of Intranasal corticosteroids in the Netherlands: an analysis from the Netherlands Pharmacovigilance Center

C Rollema, EN van Roon, C Ekhart… - Drugs-Real World …, 2022 - Springer
Background Intranasal corticosteroids are one of the cornerstone treatment options for
allergic rhinitis and chronic sinusitis complaints. Safety information in the summary of …

Pharmacology, particle deposition and drug administration techniques of intranasal corticosteroids for treating allergic rhinitis

C Rollema, EN van Roon… - Clinical & …, 2022 - Wiley Online Library
This review presents an overview of the available literature regarding intranasal
corticosteroids (INCs) for the treatment of allergic rhinitis (AR). Various treatment options …

Hypothalamic‐pituitary‐adrenal axis suppression and intranasal corticosteroid use: A systematic review and meta‐analysis

G Sampieri, A Namavarian, JJW Lee… - … Forum of Allergy & …, 2022 - Wiley Online Library
Background Intranasal corticosteroids (INCS) are used in the management of sinonasal
conditions. Use of exogenous steroids can be associated with hypothalamic‐pituitary …

A scholarly review of the safety and efficacy of intranasal corticosteroids preparations in the treatment of chronic rhinosinusitis

L Macias-Valle, AJ Psaltis - Ear, Nose & Throat Journal, 2021 - journals.sagepub.com
Objective: The purpose of this scholarly review is to present an update of the efficacy, safety,
and distribution of intranasal corticosteroids (INCS) in the context of treatment for chronic …

Impact of Inhaled and Intranasal Corticosteroids Exposure on the Risk of Ocular Hypertension and Glaucoma: A Systematic Review and Meta-Analysis

A Vinokurtseva, M Fung, E Ai Li, R Zhang… - Clinical …, 2022 - Taylor & Francis
Purpose Starting in 2019, the Global Initiative for Asthma recommended the use of inhaled
corticosteroids (ICS) as part of reliever combination therapy in patients 12 years of age and …

[HTML][HTML] Comparative efficacy and acceptability of licensed dose intranasal corticosteroids for moderate-to-severe allergic rhinitis: a systematic review and network …

KK Soe, T Krikeerati… - Frontiers in …, 2023 - frontiersin.org
No evidence shows that one intranasal corticosteroid (INCS) is better than another for
treating moderate-to-severe allergic rhinitis (AR). This network meta-analysis assessed the …

[HTML][HTML] Effectiveness of septoplasty compared to medical management in adults with obstruction associated with a deviated nasal septum: the NAIROS RCT.

S Carrie, T Fouweather, T Homer, J O'Hara… - Health Technology …, 2024 - ncbi.nlm.nih.gov
BACKGROUND The indications for septoplasty are practice-based, rather than evidence-
based. In addition, internationally accepted guidelines for the management of nasal …