Childhood and adolescent obesity have reached epidemic levels in the United States.
Currently, about 17% of US children are presenting with obesity. Obesity can affect all …

Background and aim Epidemiological data has established increasing adiposity as a risk
factor for incident asthma. However, the mechanisms underlying the association between …

Obesity is associated with the development of asthma, which is often difficult to control. To
understand the immunological pathways that lead to obesity-associated asthma, we fed …

Epidemiological studies report that overweight or obese asthmatic subjects have more
severe disease than those of a healthy weight. We postulated that accumulation of adipose …

Adipokines, factors produced by adipose tissue, may be proinflammatory (such as leptin and
resistin) or anti‐inflammatory (such as adiponectin). Effects of these adipokines on the lungs …

Rationale: Obesity is associated with increased asthma morbidity, lower drug
responsiveness to inhaled corticosteroids, and worse asthma control. However, most prior …

Background Obesity is highly prevalent in asthmatic children and associated with worse
clinical outcomes. Energy restriction to induce weight loss in asthmatic children has not …

Rationale: The burden of asthma is highest among socioeconomically disadvantaged
populations; however, its impact is differentially distributed among racial and ethnic groups …

Obese adults with asthma have an increased number of comorbidities and reduced daily life
physical activity (DLPA), which may worsen asthma symptoms. Exercise is recommended to …

Elevated levels of circulating proinflammatory cytokines are associated with obesity and
increased risk of type 2 diabetes, but the mechanism is unknown. We tested whether …