[HTML][HTML] Stem cell-based therapy for human diseases

DM Hoang, PT Pham, TQ Bach, ATL Ngo… - Signal transduction and …, 2022 - nature.com
Recent advancements in stem cell technology open a new door for patients suffering from
diseases and disorders that have yet to be treated. Stem cell-based therapy, including …

[HTML][HTML] Psoriasis between autoimmunity and oxidative stress: changes induced by different therapeutic approaches

MV Medovic, VL Jakovljevic, VI Zivkovic… - … medicine and cellular …, 2022 - ncbi.nlm.nih.gov
Psoriasis is defined as chronic, immune-mediated disease. Regardless of the development
of new therapeutic approaches, the precise etiology of psoriasis remains unknown and …

Biologics‐loaded photothermally dissolvable hyaluronic acid microneedle patch for psoriasis treatment

D Wu, X Shou, Y Yu, X Wang, G Chen… - Advanced Functional …, 2022 - Wiley Online Library
Emerging biologics, such as monoclonal antibodies (mAbs), are the most promising
treatment for psoriasis, while their effective delivery to the local inflammatory area of the skin …

Mesenchymal stem cells in fibrotic diseases—The two sides of the same coin

L Qin, N Liu, C Bao, D Yang, G Ma, W Yi… - Acta Pharmacologica …, 2023 - nature.com
Fibrosis is caused by extensive deposition of extracellular matrix (ECM) components, which
play a crucial role in injury repair. Fibrosis attributes to~ 45% of all deaths worldwide. The …

[HTML][HTML] Efficacy and safety of mesenchymal stem cell transplantation in the treatment of autoimmune diseases (rheumatoid arthritis, systemic lupus erythematosus …

L Zeng, G Yu, K Yang, W Xiang, J Li, H Chen - Stem Cells International, 2022 - hindawi.com
Objective. To evaluate the efficacy and safety of mesenchymal stem cell (MSC)
transplantation in the treatment of autoimmune diseases. Methods. The Chinese and …

HIF-overexpression and pro-inflammatory priming in human mesenchymal stromal cells improves the healing properties of extracellular vesicles in experimental …

M Gómez-Ferrer, E Amaro-Prellezo… - International journal of …, 2021 - mdpi.com
Extracellular vesicles (EVs) derived from mesenchymal stromal cells (MSCs) have
therapeutic potential in the treatment of several immune disorders, including ulcerative …

Bioprintable lung extracellular matrix hydrogel scaffolds for 3D culture of mesenchymal stromal cells

B Falcones, H Sanz-Fraile, E Marhuenda, I Mendizábal… - Polymers, 2021 - mdpi.com
Mesenchymal stromal cell (MSC)-based cell therapy in acute respiratory diseases is based
on MSC secretion of paracrine factors. Several strategies have proposed to improve this are …

An update for mesenchymal stem cell therapy in lupus nephritis

W Li, W Chen, L Sun - Kidney Diseases, 2021 - karger.com
Background: Lupus nephritis (LN) is the most severe organ manifestations of systemic lupus
erythematosus (SLE). Although increased knowledge of the disease pathogenesis has …

Potential applications of mesenchymal stem cells and their derived exosomes in regenerative medicine

M Adelipour, DM Lubman, J Kim - Expert Opinion on Biological …, 2023 - Taylor & Francis
Introduction Regenerative medicine involves the replacement of damaged cells, tissues, or
organs to restore normal function. Mesenchymal stem cells (MSCs) and exosomes secreted …

Immunomodulatory effect of MSCs and MSCs-derived extracellular vesicles in systemic lupus erythematosus

C Yang, J Sun, Y Tian, H Li, L Zhang, J Yang… - Frontiers in …, 2021 - frontiersin.org
Systemic lupus erythematosus (SLE) is a common autoimmune connective tissue disease
with unclear etiology and pathogenesis. Mesenchymal stem cell (MSC) and MSC derived …