Clinical prospect of mesenchymal stromal/stem cell-derived extracellular vesicles in kidney disease: Challenges and the way forward

M Kosanović, B Milutinović, TJ Kutzner, Y Mouloud… - Pharmaceutics, 2023 - mdpi.com
Kidney disease is a growing public health problem worldwide, including both acute and
chronic forms. Existing therapies for kidney disease target various pathogenic mechanisms; …

Human umbilical cord-derived mesenchymal stem cells ameliorate psoriasis-like dermatitis by suppressing IL-17-producing γδ T cells

Y Chen, Y Hu, X Zhou, Z Zhao, Q Yu, Z Chen… - Cell and Tissue …, 2022 - Springer
Mesenchymal stem cells (MSCs) have shown great potential in treating autoimmune
diseases due to their immunomodulatory capability, which has been verified in both animal …

Role and function of mesenchymal stem cells on fibroblast in cutaneous wound healing

K Tanaka, R Ogino, S Yamakawa, S Suda… - Biomedicines, 2022 - mdpi.com
Skin wounds often repair themselves completely over time; however, this is true only for
healthy individuals. Although various studies are being conducted to improve wound …

The promise and challenges of cell therapy for psoriasis

SM Lwin, JA Snowden… - British Journal of …, 2021 - academic.oup.com
The management of moderate‐to‐severe psoriasis has been transformed by the introduction
of biological therapies. These medicines, particularly those targeting interleukin (IL)‐17 and …

Efficacy of mesenchymal stem cells in animal models of lupus nephritis: a meta-analysis

T Zhou, C Liao, HY Li, W Lin, S Lin, H Zhong - Stem Cell Research & …, 2020 - Springer
Background Lupus nephritis is usually manifested by proteinuria, active urinary sediment,
hypertension, and renal failure and is a serious complication with more than 50 …

Evaluation of the optimal manufacturing protocols and therapeutic properties of mesenchymal stem/stromal cells derived from Wharton's jelly

M Sypecka, A Bzinkowska, D Sulejczak… - International Journal of …, 2022 - mdpi.com
Wharton's jelly (WJ) from the umbilical cord (UC) is a good source of mesenchymal
stem/stromal cells (MSCs), which can be isolated and used in therapy. Current knowledge …

[HTML][HTML] Immunomodulating profile of dental mesenchymal stromal cells: A comprehensive overview

A Paganelli, O Trubiani, F Diomede, A Pisciotta… - Frontiers in Oral …, 2021 - frontiersin.org
Dental mesenchymal stromal cells (MSCs) are multipotent cells present in dental tissues,
characterized by plastic adherence in culture and specific surface markers (CD105, CD73 …

LncRNA LYPLAL1-AS1 rejuvenates human adipose-derived mesenchymal stem cell senescence via transcriptional MIRLET7B inactivation

Y Yang, S Liu, C He, T Lv, L Zeng, F Zhang, H Chen… - Cell & Bioscience, 2022 - Springer
Background Mesenchymal stem cell (MSC) senescence is a phenotype of aging. Long
noncoding RNAs (lncRNAs) are emerging as potential key regulators of senescence …

Mesenchymal stem cells for the treatment of psoriasis: a comprehensive review

A Paganelli, E Tarentini, L Benassi… - Clinical and …, 2020 - academic.oup.com
Mesenchymal stem cells (MSCs) have recently been shown to have not only regenerative
capabilities but also immunomodulating properties. For this reason, they are currently under …

[HTML][HTML] Recent advances in single-cell view of mesenchymal stem cell in osteogenesis

F Shen, Y Shi - Frontiers in Cell and Developmental Biology, 2022 - frontiersin.org
Osteoblasts continuously replenished by osteoblast progenitor cells form the basis of bone
development, maintenance, and regeneration. Mesenchymal stem cells (MSCs) from …