Insertion of transposed elements within mammalian genes is thought to be an important
contributor to mammalian evolution and speciation. Insertion of transposed elements into …

Transforming growth factor beta-1 (TGFB1) may influence asthma by modulating allergic
airway inflammation and airway remodeling. The role of single nucleotide polymorphisms …

Background Genetic variants, underlining phenotypic diversity, are known to distribute
unevenly in the human genome. A comprehensive understanding of the distributions of …

Retrotransposons such as LINE-1 and Alu comprise> 25% of the human genome. While
global hypomethylation of these elements has been widely reported in solid tumours, their …

In a living cell, the antiparallel double-stranded helix of DNA is a dynamically changing
structure. The structure relates to interactions between and within the DNA strands, and the …

Aim: To study DNA methylation patterns of Alu Y subfamilies in schizophrenia (SCZ) and
bipolar disorder (BPD). Patients & methods: A bisulfite conversion-specific one-label …

Background Transposons (transposable elements or TEs) are DNA sequences that can
change their position within the genome. A large number of TEs have been identified in …

Background The presence of loss-of-heterozygosity (LOH) mutations in cancer cell genomes
is commonly encountered. Moreover, the occurrences of LOHs in tumor suppressor genes …

Background To complement next-generation sequencing technologies, there is a pressing
need for efficient pre-sequencing capture methods with reduced costs and DNA …

Background Schizophrenia is a major disorder with complex genetic mechanisms. Earlier,
population genetic studies revealed the occurrence of strong positive selection in the …