Advances of nanoparticles as drug delivery systems for disease diagnosis and treatment

R Liu, C Luo, Z Pang, J Zhang, S Ruan, M Wu… - Chinese chemical …, 2023 - Elsevier
Decades have passed since the first nanoparticles-base medicine was approved for human
cancer treatment, and the research and development of nanoparticles for drug delivery are …

Ferroptosis nanomedicine: clinical challenges and opportunities for modulating tumor metabolic and immunological landscape

H Yang, X Yao, Y Liu, X Shen, M Li, Z Luo - Acs Nano, 2023 - ACS Publications
Ferroptosis, a type of regulated cell death driven by iron-dependent phospholipid
peroxidation, has captured much attention in the field of nanomedicine since it was coined in …

A nanoparticulate dual scavenger for targeted therapy of inflammatory bowel disease

C Shi, J Dawulieti, F Shi, C Yang, Q Qin, T Shi… - Science …, 2022 - science.org
A therapeutic strategy that targets multiple proinflammatory factors in inflammatory bowel
disease (IBD) with minimal systemic side effects would be attractive. Here, we develop a …

Oral colon-targeted mucoadhesive micelles with enzyme-responsive controlled release of curcumin for ulcerative colitis therapy

C Zhang, J Li, M Xiao, D Wang, Y Qu, L Zou… - Chinese Chemical …, 2022 - Elsevier
Although multitudinous nanoscale drug-delivery systems (DDSs) have been recommended
to improve anti-ulcerative colitis (UC) outcomes, to enhance the mucoadhesion of …

Engineering nano-drug biointerface to overcome biological barriers toward precision drug delivery

S Waheed, Z Li, F Zhang, A Chiarini, U Armato… - Journal of …, 2022 - Springer
The rapid advancement of nanomedicine and nanoparticle (NP) materials presents novel
solutions potentially capable of revolutionizing health care by improving efficacy …

Anti‐inflammatory effect of Rhein on ulcerative colitis via inhibiting PI3K/Akt/mTOR signaling pathway and regulating gut microbiota

L Dong, H Du, M Zhang, H Xu, X Pu… - Phytotherapy …, 2022 - Wiley Online Library
This study aimed to analyze the therapeutic effect of Rhein on ulcerative colitis (UC) in mice
and its possible mechanism. LPS‐induced UC cell model and DSS‐induced UC mouse …

ROS and RNS modulation: the main antimicrobial, anticancer, antidiabetic, and antineurodegenerative mechanisms of metal or metal oxide nanoparticles

M Alavi, R Yarani - Nano Micro Biosystems, 2023 - nmb-journal.com
Severe side effects of chemotherapeutic and anti-diabetic drugs for cancer cells and type 2
diabetes (T2D) type and emerging drug resistance in pathogenic microorganisms …

Tea leaf-derived exosome-like nanotherapeutics retard breast tumor growth by pro-apoptosis and microbiota modulation

Q Chen, M Zu, H Gong, Y Ma, J Sun, S Ran… - Journal of …, 2023 - Springer
While several artificial nanodrugs have been approved for clinical treatment of breast tumor,
their long-term applications are restricted by unsatisfactory therapeutic outcomes, side …

Harnessing polymer-derived drug delivery systems for combating inflammatory bowel disease

Y Pu, X Fan, Z Zhang, Z Guo, Q Pan, W Gao… - Journal of Controlled …, 2023 - Elsevier
The inflammatory bowel disease (IBD) is incurable, chronic, recrudescent disorders in the
inflamed intestines. Current clinic treatments are challenged by systemic exposure-induced …

Recent progress in nanotechnology-based drug carriers for resveratrol delivery

C Li, Z Wang, H Lei, D Zhang - Drug delivery, 2023 - Taylor & Francis
Resveratrol is a polyphenol with diverse pharmacological activities, but its clinical efficacy is
limited due to low solubility/permeability, light-induced isomerization, auto-oxidation, and …