malERA: an updated research agenda for malaria elimination and eradication

RN Rabinovich, C Drakeley, AA Djimde, BF Hall… - PLoS …, 2017 - journals.plos.org
Achieving a malaria-free world presents exciting scientific challenges as well as
overwhelming health, equity, and economic benefits. WHO and countries are setting …

Review and drug therapy implications of glucose-6-phosphate dehydrogenase deficiency

KD Belfield, EM Tichy - The Bulletin of the American Society of …, 2018 - academic.oup.com
Purpose The pathophysiology, diagnosis, and medication-use implications of glucose-6-
phosphate dehydrogenase (G6PD) deficiency, the most common enzyme deficiency in …

Tafenoquine and G6PD: a primer for clinicians

CS Chu, DO Freedman - Journal of travel medicine, 2019 - academic.oup.com
Abstract Background Tafenoquine, an 8-aminoquinoline, is now indicated for causal
prophylaxis against all human malarias and as radical curative (anti-relapse) treatment …

Genetic variants of glucose-6-phosphate dehydrogenase and their associated enzyme activity: a systematic review and meta-analysis

DA Pfeffer, AW Satyagraha, A Sadhewa, MS Alam… - Pathogens, 2022 - mdpi.com
Low glucose-6-phosphate dehydrogenase enzyme (G6PD) activity is a key determinant of
drug-induced haemolysis. More than 230 clinically relevant genetic variants have been …

Glucose 6 Phosphate Dehydrogenase (G6PD) quantitation using biosensors at the point of first contact: a mixed method study in Cambodia

B Adhikari, R Tripura, L Dysoley, JJ Callery, TJ Peto… - Malaria Journal, 2022 - Springer
Abstract Background Quantitative measurement of Glucose-6-Phosphate Dehydrogenase
(G6PD) enzyme activity is critical to decide on appropriate treatment and provision of radical …

Performance of the Access Bio/CareStart rapid diagnostic test for the detection of glucose-6-phosphate dehydrogenase deficiency: A systematic review and meta …

B Ley, A Winasti Satyagraha, H Rahmat… - PLoS …, 2019 - journals.plos.org
Background To reduce the risk of drug-induced haemolysis, all patients should be tested for
glucose-6-phosphate dehydrogenase (G6PD) deficiency (G6PDd) prior to prescribing …

malERA: An updated research agenda for diagnostics, drugs, vaccines, and vector control in malaria elimination and eradication

malERA Refresh Consultative Panel on Tools for … - PLoS …, 2017 - journals.plos.org
Since the turn of the century, a remarkable expansion has been achieved in the range and
effectiveness of products and strategies available to prevent, treat, and control malaria …

Field evaluation of quantitative point of care diagnostics to measure glucose-6-phosphate dehydrogenase activity

MS Alam, MG Kibria, N Jahan, K Thriemer… - PloS one, 2018 - journals.plos.org
Background Glucose-6-Phosphate dehydrogenase (G6PD) deficiency is the most common
enzymopathy worldwide, no reliable bedside diagnostic tests to quantify G6PD activity exist …

Repeatability and reproducibility of a handheld quantitative G6PD diagnostic

B Ley, A Winasti Satyagraha, MG Kibria… - PLOS Neglected …, 2022 - journals.plos.org
Background The introduction of novel short course treatment regimens for the radical cure of
Plasmodium vivax requires reliable point-of-care diagnosis that can identify glucose-6 …

Methods for the field evaluation of quantitative G6PD diagnostics: a review

B Ley, G Bancone, L Von Seidlein, K Thriemer… - Malaria journal, 2017 - Springer
Individuals with glucose-6-phosphate dehydrogenase (G6PD) deficiency are at risk of
severe haemolysis following the administration of 8-aminoquinoline compounds …