Renal cell carcinoma (RCC) is the most common type of kidney cancers in adults, and
metastasis represents the major cause of mortality of RCC patients. The Y-box binding …

We have studied differentially regulated nuclear proteome of the clinical tissue specimens of
glioblastoma (GBM, WHO Grade IV) and lower grades of gliomas (Grade II and III) using …

SOX family transcription factor has emerged as a double-edged sword relating to
tumorigenesis and metastasis. Multiple studies have revealed different expression patterns …

Introduction Malignant pleural mesothelioma (MPM) is an aggressive malignancy linked to
asbestos exposure. On a genomic level, MPM is characterized by frequent chromosomal …

Evidence is accumulating that extracellular microvesicles (MV) facilitate progression and
relapse in cancer. Using a model in which MVs derived from K562 chronic myelogenous …

Background: Dysregulation of RNA binding proteins (RBPs) has been identified in multiple
malignant tumors correlated with tumor progression and occurrence. However, the function …

Prostaglandin E2 (PGE2) has been implicated in hepatocellular carcinoma cell invasion.
Recently, it was reported that Y box-binding protein 1 (YB-1) is closely correlated with …

Lung cancers and malignant pleural mesothelioma (MPM) have some of the worst 5-year
survival rates of all cancer types, primarily due to a lack of effective treatment options for …

Abnormal expression of the transcription factor Y-box-binding protein-1 (YBX1) is associated
with the proliferation, migration, aggressiveness, and stem-like properties of various …

Despite advances in the understanding of the molecular mechanisms underlying the basic
biology and pathogenesis of pediatric central nervous system (CNS) malignancies, patients …