Introduction: Prostate cancer is a leading cause of cancer-related death in men and current
treatments offer only a modest survival benefit in advanced stages of the disease. RNA …

This review discusses the role of the multifunctional DNA/RNA-binding protein YB-1 in
inflammation. YB-1 performs multiple functions in the cell depending on its location: it acts as …

Abstract Y‑box‑binding protein 1 (YB‑1) is a DNA/RNA‑binding protein and an important
transcription and translation factor in carcinogenesis. However, the biological function and …

Chemotherapy with taxanes such as paclitaxel (PTX) is a key component of triple negative
breast cancer (TNBC) treatment. PTX is used in combination with other drugs in both the …

Simple Summary Triple-negative breast cancer (TNBC) is associated with the high rates of
relapse and metastasis and poor survival. YB-1 is overexpressed in TNBC tumor tissues. In …

Approximately 60% of cancer patients receive curative or palliative radiation. Despite the
significant role of radiotherapy (RT) as a curative approach for many solid tumors, tumor …

Adipocytokines such as leptin and adiponectin have functions in metabolism as well as the
development and progression of various types of malignancies. However, little is known …

Y-box binding protein-1 (YB-1) has been identified as an oncoprotein in various
malignancies. The aim of this study was to investigate the biological role of YB-1 and its …

Abstract Y-box-binding protein 1 (YB-1) is a DNA/RNA binding protein increasingly
implicated in the regulation of cancer cell biology. Normally located in the cytoplasm …

Cold shock domain proteins are characterized by the presence of one or more evolutionarily
conserved cold shock domains, which each possess two nucleic acid-binding motifs. These …