Familial Mediterranean fever (FMF) is the most common monogenic periodic fever syndrome
and characterized by recurrent episodes of fever, serositis, arthritis, dermal manifestations …

Familial Mediterranean fever (FMF) is an autoinflammatory disease manifested by
inflammatory attacks of peritonitis, pleuritis, pericarditis accompanied by fever and arthritis …

Objectives Colchicine is the main treatment for FMF. Although a number of individuals with
FMF are intolerant/resistant to colchicine, there is no standard definition of colchicine …

Post-hoc subgroup analysis of the negative trial of interleukin-1β receptor antagonist
(IL1RA) for septic shock suggested that patients with features of macrophage activation …

İntroduction: Familial Mediterranean fever (FMF) is a hereditary auto-inflammatory disease
characterized by recurrent fever and serosal inflammation. Anti-interleukin-1 (Anti-IL-1) …

Aim To determine the factors associated with colchicine resistance and the effect of
colchicine resistance on health‐related quality of life (QoL) in patients with familial …

Objective Familial Mediterranean fever (FMF) is the most common inherited monogenic
autoinflammatory disease worldwide. It is caused by loss-of-function mutations in the MEFV …

Unprovoked activation of innate immune pathways and increased secretion of interleukin
(IL)-1β and IL-18 are responsible for the protean clinical manifestations and the marked …

Autoinflammatory diseases were originally defined as a group of monogenic disorders
associated with seemingly unprovoked inflammatory episodes mediated mainly by the …

As an autosomal recessive autoinflammatory disease, treatment of Familial Mediterranean
fever (FMF) has still gaps. Clinical studies are proving the safety and efficacy of colchicine in …