Oliynyk I, Varelogianni G, Roomans GM, Johannesson M. Effect of duramycin on chloride
transport and intracellular calcium concentration in cystic fibrosis and non‐cystic fibrosis …

Effective mucociliary clearance (MCC) depends in part on adequate airway surface liquid
(ASL) volume to maintain an appropriate periciliary fluid height that allows normal ciliary …

Membrane potential (V m)-, Na+-, or Ca2+-sensitive fluorescent dyes were used to analyze
changes in V m or intracellular ion concentrations in airway epithelial cells treated with …

PLUNC (palate, lung and nasal epithelium clone)-associated gene originally referred to one
gene, but now has been extended to represent a gene family that consists of a number of …

Airway epithelium is constantly presented with injurious signals, yet under healthy
circumstances, the epithelium maintains its innate immune barrier and mucociliary elevator …

Cystic fibrosis (CF) is the commonest genetic cause of bronchiectasis in the Caucasian
population. Since identification of the putative gene in 1989, the molecular basis of the …

α-klotho (KL) is an anti-aging protein and has been shown to exert anti-inflammatory and
anti-oxidative effects in the lung and pulmonary diseases such as chronic obstructive …

Mucociliary clearance is critically important in protecting the airways from infection and from
the harmful effects of smoke and various inspired substances known to induce oxidative …

The airway acts as the first defense against inhaled pathogens and particulate matter from
the environment. One major way for the airway to clear inhaled foreign objects is through …

Airway dehydration causes mucus stasis and bacterial overgrowth in cystic fibrosis (CF),
resulting in recurrent respiratory infections and exacerbations. Strategies to rehydrate airway …