Regulation of cystic fibrosis transmembrane regulator (CFTR) and epithelial sodium channel
(ENaC) in airway epithelia strongly influences the rate of mucociliary clearance (MCC) by …

5, 756, 121 A 5/1998 Bracken 5, 756, 353 A 5/1998 Debs 5, 759, 571 A 6/1998 Hersch et al.
5, 766, 627 A 6/1998 Sankaram et al. 5, 785, 987 A 7/1998 Hope et al. 5, 795, 589 A 8/1998 …

Airway epithelium has been shown to exhibit intracellular calcium waves after mechanical
stimulation. Two classes of mechanism have been proposed to explain calcium wave …

(57) ABSTRACT A system for treating or providing prophylaxus against a pulmonary
infection is disclosed comprising: a) a pharma ceutical formulation comprising a mixture of …

In cystic fibrosis (CF), excessive furin activity plays a critical role in the activation of the
epithelial sodium channel (ENaC), dysregulation of which contributes to airway dehydration …

“Exercise-induced bronchoconstriction (EIB) and exercise induced asthma are the terms
used to describe the transient increase in airways resistance that follows vigorous exercise.” …

Regulation of periciliary liquid (PCL) depth is of central importance to mucociliary clearance
by the airway epithelium. Without adequate hydration mucociliary transport would cease …

Staphylococcus aureus (S. aureus) is a human commensal and an opportunistic pathogen
that may affect the gastrointestinal tract, the heart, bones, skin or the respiratory tract. S …

(63) Continuation of application No. 15/205,918, filed on(Continued) Jul. 8, 2016, which is a
continuation of application No. 14/987,508, filed on Jan. 4, 2016, now Pat. No. OTHER …

Using human airway epithelial cell lines (ie NCI-H441 and Calu-3) as well as human
alveolar epithelial type I-like (ATI) cells in primary culture, we studied the contribution of the …