OTUD1 activates caspase‐independent and caspase‐dependent apoptosis by promoting AIF nuclear translocation and MCL1 degradation

Q Luo, X Wu, P Zhao, Y Nan, W Chang… - Advanced …, 2021 - Wiley Online Library
Apoptosis‐inducing factor (AIF) plays a dual role in regulating cell survival and apoptosis,
acting as a prosurvival factor in mitochondria via its NADH oxidoreductase activity and …

LncRNA TUG1 promotes cisplatin resistance in esophageal squamous cell carcinoma cells by regulating Nrf2

Z Zhang, R Xiong, C Li, M Xu… - Acta Biochimica et …, 2019 - academic.oup.com
Esophageal squamous cell carcinoma (ESCC) is a common malignancy with poor
prognosis. The drug resistance compromises the efficacy of chemotherapy for ESCC. Long …

Exosomal lncRNA FAM225A accelerates esophageal squamous cell carcinoma progression and angiogenesis via sponging miR‐206 to upregulate NETO2 and …

C Zhang, Y Luo, J Cao, X Wang, Z Miao… - Cancer …, 2020 - Wiley Online Library
Esophageal cancer is one of the leading causes of cancer‐related deaths worldwide.
FAM225A is a novel lncRNA, only has been explored in nasopharyngeal carcinoma …

[HTML][HTML] Integrin α5 promotes migration and cisplatin resistance in esophageal squamous cell carcinoma cells

S Hou, W Jin, W Xiao, B Deng, D Wu, J Zhi… - American journal of …, 2019 - ncbi.nlm.nih.gov
Cisplatin, as one of the front-line chemotherapeutic drugs, is employed for the treatment of
esophageal squamous cell carcinoma (ESCC). However, the occurrence of cisplatin …

[HTML][HTML] Expression of Insulin-Like Growth Factor Binding Protein-5 (IGFBP5) Reverses Cisplatin-Resistance in Esophageal Carcinoma

D Chan, Y Zhou, CH Chui, KH Lam, S Law, AS Chan… - Cells, 2018 - mdpi.com
Cisplatin (CDDP) is one of the front-line chemotherapeutic drugs used in the treatment of
esophageal squamous cell carcinoma (ESCC). Occurrence of resistance to CDDP has …

[HTML][HTML] MELK predicts poor prognosis and promotes metastasis in esophageal squamous cell carcinoma via activating the NF‑κB pathway

J Ye, W Deng, Y Zhong, H Liu… - International …, 2022 - spandidos-publications.com
Esophageal squamous cell carcinoma (ESCC) is one of the most common malignancies
worldwide with a low 5‑year survival rate due to the lack of effective therapeutic strategies …

[HTML][HTML] Downregulation of MUTYH contributes to cisplatin‑resistance of esophageal squamous cell carcinoma cells by promoting Twist‑mediated EMT

Y Guo, Y Jia, S Wang, N Liu, D Gao… - Oncology …, 2019 - spandidos-publications.com
Acquired resistance to cisplatin (CDDP) in esophageal squamous cell carcinoma (ESCC)
remains a major challenge in cancer therapy. Although progress has been made in …

[HTML][HTML] Survival based radiographic-grouping for esophageal squamous cell carcinoma may impact clinical T stage

W Cai, JJ Lu, R Xu, P Xin, J Xin, Y Chen, B Gao… - Oncotarget, 2018 - ncbi.nlm.nih.gov
Most patients diagnosed with thoracic esophageal squamous cell carcinoma (ESCC) have
progressed beyond surgical resection as a therapeutic option. Difficulties in the proper …

[HTML][HTML] Construction and evaluation of prognostic models for esophageal cancer patients with distant and non-distant metastases: providing a reference process for …

M Zhang, M Cui, Q Zuo, L Wang, J Wang… - Journal of …, 2021 - ncbi.nlm.nih.gov
Background Although the current treatment for esophageal cancer has great technological
progress, the 5-year survival rate of patients is not optimistic. About 70% of patients with …

Factores pronósticos en el cáncer de esófago. Nomograma pronóstico de supervivencia

L Martí Gelonch - 2022 - ekoizpen-zientifikoa.ehu.eus
Introducción: El cáncer de esófago representa la séptima neoplasia más frecuente y la sexta
causa de muerte por cáncer a nivel mundial. Debido a su historia natural, suele …