Vaccine adjuvants: mechanisms and platforms
T Zhao, Y Cai, Y Jiang, X He, Y Wei, Y Yu… - Signal transduction and …, 2023 - nature.com
Adjuvants are indispensable components of vaccines. Despite being widely used in
vaccines, their action mechanisms are not yet clear. With a greater understanding of the …
vaccines, their action mechanisms are not yet clear. With a greater understanding of the …
Emerging concepts in the science of vaccine adjuvants
B Pulendran, P S. Arunachalam… - Nature Reviews Drug …, 2021 - nature.com
Adjuvants are vaccine components that enhance the magnitude, breadth and durability of
the immune response. Following its introduction in the 1920s, alum remained the only …
the immune response. Following its introduction in the 1920s, alum remained the only …
An overview of vaccine adjuvants: current evidence and future perspectives
Vaccinations are one of the most important preventive tools against infectious diseases.
Over time, many different types of vaccines have been developed concerning the antigen …
Over time, many different types of vaccines have been developed concerning the antigen …
Non-viral COVID-19 vaccine delivery systems
The novel corona virus termed severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) has spread throughout the globe at a formidable speed, causing tens of millions of …
CoV-2) has spread throughout the globe at a formidable speed, causing tens of millions of …
Delivery strategies for mRNA vaccines
S Ramachandran, SR Satapathy, T Dutta - Pharmaceutical medicine, 2022 - Springer
The therapeutic potential for messenger RNA (mRNA) in infectious diseases and cancer
was first realized almost three decades ago, but only in 2018 did the first lipid nanoparticle …
was first realized almost three decades ago, but only in 2018 did the first lipid nanoparticle …
TREM2 macrophages induced by human lipids drive inflammation in acne lesions
Acne affects 1 in 10 people globally, often resulting in disfigurement. The disease involves
excess production of lipids, particularly squalene, increased growth of Cutibacterium acnes …
excess production of lipids, particularly squalene, increased growth of Cutibacterium acnes …
New-age vaccine adjuvants, their development, and future perspective
In the present scenario, immunization is of utmost importance as it keeps us safe and
protects us from infectious agents. Despite the great success in the field of vaccinology …
protects us from infectious agents. Despite the great success in the field of vaccinology …
[HTML][HTML] Vaccination in the elderly: the challenge of immune changes with aging
The unprecedented increase of life expectancy challenges society to protect the elderly from
morbidity and mortality making vaccination a crucial mean to safeguard this population …
morbidity and mortality making vaccination a crucial mean to safeguard this population …
Lipid-based nanoparticles for delivery of vaccine adjuvants and antigens: toward multicomponent vaccines
D Chatzikleanthous, DT O'Hagan… - Molecular …, 2021 - ACS Publications
Despite the many advances that have occurred in the field of vaccine adjuvants, there are
still unmet needs that may enable the development of vaccines suitable for more …
still unmet needs that may enable the development of vaccines suitable for more …
Hemagglutinin-stem nanoparticles generate heterosubtypic influenza protection
HM Yassine, JC Boyington, PM McTamney, CJ Wei… - Nature medicine, 2015 - nature.com
The antibody response to influenza is primarily focused on the head region of the
hemagglutinin (HA) glycoprotein, which in turn undergoes antigenic drift, thus necessitating …
hemagglutinin (HA) glycoprotein, which in turn undergoes antigenic drift, thus necessitating …