Cardiac transplantation has become limited by a critical shortage of suitable organs from
brain-dead donors. Reports describing the successful clinical transplantation of hearts …

Background Orthotopic heart transplantation is the gold-standard long-term treatment for
medically refractive end-stage heart failure. However, suitable cardiac donors are scarce …

Heart transplantation remains the preferred option for improving quality of life and survival
for patients suffering from end-stage heart failure. Unfortunately, insufficient supply of …

Despite major therapeutic advances, heart failure, as a non-communicable disease, remains
a life-threatening disorder, with 26 million patients worldwide, causing more deaths than …

Objective The adoption of hearts from donation after circulatory death (DCD) is a promising
approach for the shortage of suitable organs in heart transplantation. However, DCD hearts …

In donation after circulatory death (DCD), cardiac grafts are subjected to warm ischemia in
situ, prior to a brief period of cold, static storage (CSS) at procurement, and ex situ …

Hearts donated following circulatory death (DCD) may represent an additional source of
organs for transplantation; however, the impact of donor extubation on the DCD heart has …

De forma universal, el gran problema de los trasplantes es la escasez de órganos. Cada
año aumenta la separación entre oferta y demanda, provocando que muchos pacientes …

Background Despite major therapeutic advances, heart failure remains a life-threatening
disorder, with 26 million patients worldwide, causing more deaths than cancer as a non …

The extracellular matrix (ECM) plays a key role in the viability and survival of implanted
human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs). We …